Characterization of Pulmonary Nodules Based on Features of Margin Sharpness and Texture.

Lung cancer is the leading cause of cancer-related deaths in the world, and one of its manifestations occurs with the appearance of pulmonary nodules. The classification of pulmonary nodules may be a complex task to specialists due to temporal, subjective, and qualitative aspects. Therefore, it is i...

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Publicado en:Journal of Digital Imaging Vol. 31; no. 4; pp. 451 - 464
Autores principales: Ferreira, José Raniery, Oliveira, Marcelo Costa, de Azevedo-Marques, Paulo Mazzoncini
Formato: equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Aug2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2018
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-017-0029-8
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        atl: Characterization of Pulmonary Nodules Based on Features of Margin Sharpness and Texture.
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          Ferreira, José Raniery
          Oliveira, Marcelo Costa
          de Azevedo-Marques, Paulo Mazzoncini
        affil: Center of Imaging Sciences and Medical Physics, Ribeirão Preto Medical School, University of São Paulo, Av. dos Bandeirantes, 3900, Monte Alegre, 14049-900, Ribeirão Preto, São Paulo, Brazil
      sug:
        subj:
          Lung Diseases Classification
          Tomography, X-Ray Computed
          Machine Learning Methods
          ROC Curve
          Sensitivity and Specificity
          Algorithms
          Decision Trees
      ab: Lung cancer is the leading cause of cancer-related deaths in the world, and one of its manifestations occurs with the appearance of pulmonary nodules. The classification of pulmonary nodules may be a complex task to specialists due to temporal, subjective, and qualitative aspects. Therefore, it is important to integrate computational tools to the early pulmonary nodule classification process, since they have the potential to characterize objectively and quantitatively the lesions. In this context, the goal of this work is to perform the classification of pulmonary nodules based on image features of texture and margin sharpness. Computed tomography scans were obtained from a publicly available image database. Texture attributes were extracted from a co-occurrence matrix obtained from the nodule volume. Margin sharpness attributes were extracted from perpendicular lines drawn over the borders on all nodule slices. Feature selection was performed by different algorithms. Classification was performed by several machine learning classifiers and assessed by the area under the receiver operating characteristic curve, sensitivity, specificity, and accuracy. Highest classification performance was obtained by a random forest algorithm with all 48 extracted features. However, a decision tree using only two selected features obtained statistically equivalent performance on sensitivity and specificity.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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