Minimisation of Signal Intensity Differences in Distortion Correction Approaches of Brain Magnetic Resonance Diffusion Tensor Imaging.

Objectives: To evaluate the effects of signal intensity differences between the b0 image and diffusion tensor imaging (DTI) in the image registration process.Methods: To correct signal intensity differences between the b0 image and DTI data, a simple image intensity compensation (SIMIC) method, whic...

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Publicado en:European Radiology Vol. 28; no. 10; pp. 4314 - 4324
Autores principales: Lee, Dong-Hoon, Lee, Do-Wan, Henry, David, Park, Hae-Jin, Han, Bong-Soo, Woo, Dong-Cheol
Formato: Journal Article
Publicado: Springer Nature Oct2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2018
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00330-018-5382-6
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        atl: Minimisation of Signal Intensity Differences in Distortion Correction Approaches of Brain Magnetic Resonance Diffusion Tensor Imaging.
      aug:
        au:
          Lee, Dong-Hoon
          Lee, Do-Wan
          Henry, David
          Park, Hae-Jin
          Han, Bong-Soo
          Woo, Dong-Cheol
        affil: Faculty of Health Sciences and Brain & Mind Centre, The University of Sydney, Sydney, New South Wales, Australia
      sug:
        subj:
          Magnetic Resonance Imaging Methods
          Brain
          Brain Pathology
          Telencephalon
          Algorithms
          Telencephalon Pathology
      ab: Objectives: To evaluate the effects of signal intensity differences between the b0 image and diffusion tensor imaging (DTI) in the image registration process.Methods: To correct signal intensity differences between the b0 image and DTI data, a simple image intensity compensation (SIMIC) method, which is a b0 image re-calculation process from DTI data, was applied before the image registration. The re-calculated b0 image (b0ext) from each diffusion direction was registered to the b0 image acquired through the MR scanning (b0nd) with two types of cost functions and their transformation matrices were acquired. These transformation matrices were then used to register the DTI data. For quantifications, the dice similarity coefficient (DSC) values, diffusion scalar matrix, and quantified fibre numbers and lengths were calculated.Results: The combined SIMIC method with two cost functions showed the highest DSC value (0.802 ± 0.007). Regarding diffusion scalar values and numbers and lengths of fibres from the corpus callosum, superior longitudinal fasciculus, and cortico-spinal tract, only using normalised cross correlation (NCC) showed a specific tendency toward lower values in the brain regions.Conclusion: Image-based distortion correction with SIMIC for DTI data would help in image analysis by accounting for signal intensity differences as one additional option for DTI analysis.Key Points: • We evaluated the effects of signal intensity differences at DTI registration. • The non-diffusion-weighted image re-calculation process from DTI data was applied. • SIMIC can minimise the signal intensity differences at DTI registration.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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