Evaluation of T categories for pure ground-glass nodules with semi-automatic volumetry: is mass a better predictor of invasive part size than other volumetric parameters?
Objectives: This study aimed to investigate the diagnostic advantage of nodule mass in differentiating invasive pulmonary adenocarcinomas (IPAs) among pure ground-glass nodules (pGGNs) over other volumetric measurements. Another aim of this study was to analyse the correlation between volumetric mea...
| Publicado en: | European Radiology Vol. 28; no. 10; pp. 4288 - 4296 |
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| Autores principales: | , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Oct2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131578493&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 131578493 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Oct2018 vid: 28 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 131578493 131578493 NLM29713766 10.1007/s00330-018-5440-0 NLM29713766 131578493 ppf: 4288 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Evaluation of T categories for pure ground-glass nodules with semi-automatic volumetry: is mass a better predictor of invasive part size than other volumetric parameters? aug: au: Kim, Hyungjin Goo, Jin Mo Park, Chang Min affil: Department of Radiology, Seoul National University College of Medicine, and Institute of Radiation Medicine, Seoul National University Medical Research Center, 101, Daehak-ro, Jongno-gu, 03080, Seoul, Korea sug: subj: Tomography, X-Ray Computed Methods Female ROC Curve Middle Age Male Aged Predictive Value of Tests Contrast Media Adult Retrospective Design Middle Aged: 45-64 years Aged: 65+ years Adult: 19-44 years Female Male ab: Objectives: This study aimed to investigate the diagnostic advantage of nodule mass in differentiating invasive pulmonary adenocarcinomas (IPAs) among pure ground-glass nodules (pGGNs) over other volumetric measurements. Another aim of this study was to analyse the correlation between volumetric measurements on computed tomography (CT) scans and the pathological invasive component size.Methods: This Institutional Review Board-approved retrospective study included 117 patients (men:women = 53:64; mean age, 57.3 years) with 117 pGGNs. Semi-automatic segmentation was performed for all nodules, and volumetric measurements, such as nodule volume, attenuation, mass, two-dimensional (2D) average diameter and three-dimensional (3D) longest diameter, were obtained. Receiver operating characteristic (ROC) curve analyses were performed to evaluate the diagnostic performances of the volumetric parameters in discriminating IPAs. Spearman correlation coefficients were calculated between the volumetric measurements and the invasive component size.Results: Area under the ROC curve for mass was 0.792 (95% CI, 0.691-0.872) in non-enhanced CT and 0.730 (95% CI, 0.607-0.832) in contrast-enhanced CT. Nodule mass was not superior to 2D average diameter for the differentiation of IPAs in both non-enhanced (0.792 vs 0.780; p = 0.501) CT and contrast-enhanced CT scans (0.730 vs 0.700; p = 0.319). The correlation between the volumetric measurements (mass, 3D longest diameter and 2D average diameter) and the invasive component size was moderate (Spearman's rho, 0.401-0.422) in non-enhanced CT and weak (Spearman's rho, 0.276-0.310) in contrast-enhanced CT.Conclusions: Nodule mass measurement had no strength over other volumetric parameters for the prediction of pathological invasiveness in the diagnosis of pGGNs.Key Points: • Mass is not superior to other volumetric measurements for the diagnosis of pure ground-glass nodules. • Mass and two-dimensional average diameter exhibited comparable performance for the discrimination of invasive adenocarcinomas among pure ground-glass nodules. • The diagnostic performance of volumetric measurements was lower on contrast-enhanced CT scans. • The correlation between the volumetric measurements and the invasive component size was moderate on non-enhanced CT scans and weak on contrast-enhanced CT scans. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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