Standardization of Small Animal Imaging-Current Status and Future Prospects.

The benefit of small animal imaging is directly linked to the validity and reliability of the collected data. If the data (regardless of the modality used) are not reproducible and/or reliable, then the outcome of the data is rather questionable. Therefore, standardization of the use of small animal...

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Publicado en:Molecular Imaging & Biology Vol. 20; no. 5; pp. 716 - 732
Autores principales: Mannheim, Julia G., Kara, Firat, Doorduin, Janine, Fuchs, Kerstin, Reischl, Gerald, Liang, Sayuan, Verhoye, Marleen, Gremse, Felix, Mezzanotte, Laura, Huisman, Marc C.
Formato: research Journal Article
Publicado: Springer Nature Oct2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2018
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      pub: Springer Nature
      place: New York, New York
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        atl: Standardization of Small Animal Imaging-Current Status and Future Prospects.
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          Mannheim, Julia G.
          Kara, Firat
          Doorduin, Janine
          Fuchs, Kerstin
          Reischl, Gerald
          Liang, Sayuan
          Verhoye, Marleen
          Gremse, Felix
          Mezzanotte, Laura
          Huisman, Marc C.
        affil: Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tuebingen, Roentgenweg 13, 72076, Tuebingen, Germany
      sug:
        subj:
          Diagnostic Imaging Standards
          Weights and Measures
          Phantoms, Imaging
          Human
          Animal Studies
          Image Processing, Computer Assisted
      ab: The benefit of small animal imaging is directly linked to the validity and reliability of the collected data. If the data (regardless of the modality used) are not reproducible and/or reliable, then the outcome of the data is rather questionable. Therefore, standardization of the use of small animal imaging equipment, as well as of animal handling in general, is of paramount importance. In a recent paper, guidance for efficient small animal imaging quality control was offered and discussed, among others, the use of phantoms in setting up a quality control program (Osborne et al. 2016). The same phantoms can be used to standardize image quality parameters for multi-center studies or multi-scanners within center studies. In animal experiments, the additional complexity due to animal handling needs to be addressed to ensure standardized imaging procedures. In this review, we will address the current status of standardization in preclinical imaging, as well as potential benefits from increased levels of standardization.
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        research
        Journal Article
      ougenre: Article
    language: English
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