Association between quality of life and clinical characteristics in patients with morphea.
Background: Morphea can lead to considerable cosmetic or functional impairment; nevertheless, health-related quality of life (HRQoL) is rarely documented in adult morphea patients.Objective: To investigate the impact of morphea on HRQoL and to identify determinants of impaired HRQoL.Methods: A cross...
| Publicado en: | Quality of Life Research Vol. 27; no. 10; pp. 2525 - 2533 |
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| Autores principales: | , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Oct2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131820172&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 131820172 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09629343 GPQ jtl: Quality of Life Research issn: 09629343 maglogo: N pubinfo: dt: Oct2018 vid: 27 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 131820172 131820172 NLM29922914 10.1007/s11136-018-1897-1 NLM29922914 131820172 ppf: 2525 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Association between quality of life and clinical characteristics in patients with morphea. aug: au: Bali, G. Kárpáti, S. Sárdy, M. Brodszky, V. Hidvégi, B. Rencz, F. affil: Department of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Mária u. 41., 1085, Budapest, Hungary sug: subj: Pruritus Pathology Scleroderma, Circumscribed Pathology Skin Pathology Quality of Life Psychosocial Factors Scleroderma, Circumscribed Psychosocial Factors Europe Female Young Adult Severity of Illness Indices Cross Sectional Studies Adult Middle Age Prospective Studies Aged Health Status Mental Health Aged, 80 and Over Male Scales Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Female Male ab: Background: Morphea can lead to considerable cosmetic or functional impairment; nevertheless, health-related quality of life (HRQoL) is rarely documented in adult morphea patients.Objective: To investigate the impact of morphea on HRQoL and to identify determinants of impaired HRQoL.Methods: A cross-sectional study has been carried out among adult morphea patients. HRQoL was evaluated by the Dermatology Life Quality Index (DLQI). The modified Localised Scleroderma Skin Severity Index (mLoSSI) and the Localised Scleroderma Damage Index (LoSDI) were applied to evaluate disease activity and damage, respectively. Physician Global Assessment of Activity and Damage (PGA-A, PGA-D) were also completed. Determinants of HRQoL were analysed by multiple regression.Results: A total of 101 patients (84% females) entered the study, with a mean age of 56.8 ± 14.8 years. Median mLoSSI, LoSDI, PGA-A and PGA-D scores were 8, 5, 9 and 9 points, respectively. Patients with generalised localised (51%) and plaque-type morphea (45%) had median total DLQI scores of 4 and 1, respectively. Embarrassment (53%), itchy or painful skin (46%), and clothing issues (43%) were the most commonly reported problems in the DLQI. Female gender, generalised morphea, higher disease activity (PGA-A score) and involvement of hands and/or feet were significant predictors of impaired HRQoL (p < 0.05).Conclusion: This study represents the largest sample of adult morphea patients surveyed about their HRQoL in Europe. The frequent occurrence of embarrassment warrants an increased attention to improve patients' mental health. Care must be taken in case of involvement of functionally sensitive areas, as these cases might require more intensive treatment. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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