Proposing New RadLex Terms by Analyzing Free-Text Mammography Reports.

After years of development, the RadLex terminology contains a large set of controlled terms for the radiology domain, but gaps still exist. We developed a data-driven approach to discover new terms for RadLex by mining a large corpus of radiology reports using natural language processing (NLP) metho...

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Publicado en:Journal of Digital Imaging Vol. 31; no. 5; pp. 596 - 604
Autores principales: Bulu, Hakan, Rubin, Daniel L., Sippo, Dorothy A., Lee, Janie M., Burnside, Elizabeth S.
Formato: algorithm forms research tables/charts Journal Article
Publicado: Springer Nature Oct2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2018
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      pub: Springer Nature
      place: New York, New York
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        atl: Proposing New RadLex Terms by Analyzing Free-Text Mammography Reports.
      aug:
        au:
          Bulu, Hakan
          Rubin, Daniel L.
          Sippo, Dorothy A.
          Lee, Janie M.
          Burnside, Elizabeth S.
        affil: Department of Radiology and Department of Biomedical Data Science, Medical School Office Building (MSOB), Stanford University, 1265 Welch Road, X383, 94305-5464, Stanford, CA, USA
      sug:
        subj:
          Mammography
          Software
          Data Mining
          Algorithms
          Human
          Reports
          Sensitivity and Specificity
          Radiologists
          Predictive Value of Tests
          Academic Medical Centers
          Precision
      ab: After years of development, the RadLex terminology contains a large set of controlled terms for the radiology domain, but gaps still exist. We developed a data-driven approach to discover new terms for RadLex by mining a large corpus of radiology reports using natural language processing (NLP) methods. Our system, developed for mammography, discovers new candidate terms by analyzing noun phrases in free-text reports to extend the mammography part of RadLex. Our NLP system extracts noun phrases from free-text mammography reports and classifies these noun phrases as “Has Candidate RadLex Term” or “Does Not Have Candidate RadLex Term.” We tested the performance of our algorithm using 100 free-text mammography reports. An expert radiologist determined the true positive and true negative RadLex candidate terms. We calculated precision/positive predictive value and recall/sensitivity metrics to judge the system’s performance. Finally, to identify new candidate terms for enhancing RadLex, we applied our NLP method to 270,540 free-text mammography reports obtained from three academic institutions. Our method demonstrated precision/positive predictive value of 0.77 (159/206 terms) and a recall/sensitivity of 0.94 (159/170 terms). The overall accuracy of the system is 0.80 (235/293 terms). When we ran our system on the set of 270,540 reports, it found 31,800 unique noun phrases that are potential candidates for RadLex. Our data-driven approach to mining radiology reports can identify new candidate terms for expanding the breast imaging lexicon portion of RadLex and may be a useful approach for discovering new candidate terms from other radiology domains.
      pubtype: Academic Journal
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    language: English
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