Automatische Umplanung von VMAT-Plänen für verschiedene Bestrahlungsgeräte: Ein Template-basierter Ansatz mit beschränkter Optimierung.
Purpose: To investigate a new automatic template-based replanning approach combined with constrained optimization, which may be highly useful for a rapid plan transfer for planned or unplanned machine breakdowns. This approach was tested for prostate cancer (PC) and head-and-neck cancer (HNC) cases....
| Publicado en: | Strahlentherapie und Onkologie Vol. 194; no. 10; pp. 921 - 929 |
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| Autores principales: | , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Oct2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=132002110&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 132002110 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01797158 NZE jtl: Strahlentherapie und Onkologie issn: 01797158 maglogo: N pubinfo: dt: Oct2018 vid: 194 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 132002110 132002110 NLM29846751 10.1007/s00066-018-1319-x NLM29846751 132002110 ppf: 921 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Automatische Umplanung von VMAT-Plänen für verschiedene Bestrahlungsgeräte: Ein Template-basierter Ansatz mit beschränkter Optimierung. aug: au: Künzel, Luise A. Dohm, Oliver S. Alber, Markus Zips, Daniel Thorwarth, Daniela affil: Section for Biomedical Physics, Department of Radiation Oncology, University Hospital Tübingen, 72076, Tübingen, Germany sug: subj: Radiotherapy, Conformal Equipment and Supplies Prostatic Neoplasms Radiotherapy Radiotherapy, Computer-Assisted Methods Radiotherapy, Conformal Methods Otorhinolaryngologic Neoplasms Radiotherapy Equipment Failure Male Rectum Radiation Effects Equipment Design Spinal Cord Radiation Effects Parotid Gland Radiation Effects Radiation Dosage Bladder Radiation Effects OARS Multidimensional Functional Assessment Questionnaire Male ab: Purpose: To investigate a new automatic template-based replanning approach combined with constrained optimization, which may be highly useful for a rapid plan transfer for planned or unplanned machine breakdowns. This approach was tested for prostate cancer (PC) and head-and-neck cancer (HNC) cases.Methods: The constraints of a previously optimized volumetric modulated arc therapy (VMAT) plan were used as a template for automatic plan reoptimization for different accelerator head models. All plans were generated using the treatment planning system (TPS) Hyperion. Automatic replanning was performed for 16 PC cases, initially planned for MLC1 (4 mm MLC) and reoptimized for MLC2 (5 mm) and MLC3 (10 mm) and for 19 HNC cases, replanned from MLC2 to MLC3. EUD, Dmean, D2%, and D98% were evaluated for targets; for OARs EUD and D2% were analyzed. Replanning was considered successful if both plans fulfilled equal constraints.Results: All prostate cases were successfully replanned. The mean relative target EUD deviation was -0.15% and -0.57% for replanning to MLC2 and MLC3, respectively. OAR sparing was successful in all cases. Replanning of HNC cases from MLC2 to MLC3 was successful in 16/19 patients with a mean decrease of -0.64% in PTV60 EUD. In three cases target doses were substantially decreased by up to -2.58% (PTV60) and -3.44% (PTV54), respectively. Nevertheless, OAR sparing was always achieved as planned.Conclusions: Automatic replanning of VMAT plans for a different treatment machine by using pre-existing constraints as a template for a reoptimization is feasible and successful in terms of equal constraints. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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