Plasma metabolomic profiling of a ketamine and placebo crossover trial of major depressive disorder and healthy control subjects.

(R,S)-Ketamine produces rapid, robust, and sustained antidepressant effects in major depressive disorder. Specifically, its pharmacological efficacy in treatment refractory depression is considered a major breakthrough in the field. However, the mechanism of action of ketamine’s rapid effect remains...

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Publicado en:	Psychopharmacology Vol. 235; no. 10; pp. 3017 - 3031
Autores principales:	Moaddel, Ruin, Shardell, Michelle, Khadeer, Mohammed, Lovett, Jacqueline, Kadriu, Bashkim, Ravichandran, Sarangan, Morris, Patrick J., Yuan, Peixiong, Thomas, Craig J., Gould, Todd D., Ferrucci, Luigi, Zarate, Carlos A.
Formato:	Journal Article
Publicado:	Springer Nature Oct2018
Acceso en línea:	Ver este registro en EBSCOhost