Intranasal Helicobacter pylori infection in patients with chronic rhinosinusitis with polyposis.

Objective: To determine the prevalence of Helicobacter pylori infection in nasal biopsy specimens from patients with chronic rhinosinusitis with polyposis versus control patients, and to assess the correlations between H pylori infection identified in the nasal tissue and patients' sociodemographic...

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Publicado en:Journal of Laryngology & Otology Vol. 132; no. 9; pp. 816 - 822
Autores principales: Siupsinskiene, N, Katutiene, I, Jonikiene, V, Janciauskas, D, Vaitkus, S
Formato: pictorial research tables/charts Journal Article
Publicado: Cambridge University Press Sep2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2018
      vid: 132
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      pub: Cambridge University Press
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        10.1017/S0022215118001299
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        atl: Intranasal Helicobacter pylori infection in patients with chronic rhinosinusitis with polyposis.
      aug:
        au:
          Siupsinskiene, N
          Katutiene, I
          Jonikiene, V
          Janciauskas, D
          Vaitkus, S
        affil: Faculty of Health Sciences, Klaipeda University, Lithuania
      sug:
        subj:
          Nose Pathology
          Rhinosinusitis Complications
          Nasal Polyps Complications
          Helicobacter Infections Diagnosis
          Biopsy Methods
          Gastroesophageal Reflux
          Human
          Prevalence
          Surgery, Otorhinolaryngologic Methods
          Rhinosinusitis Surgery
          Nasal Polyps Surgery
          Nasal Septum Surgery
          Histological Techniques
          Urease
          Hypertrophy
          Larynx Pathology
      ab: Objective: To determine the prevalence of Helicobacter pylori infection in nasal biopsy specimens from patients with chronic rhinosinusitis with polyposis versus control patients, and to assess the correlations between H pylori infection identified in the nasal tissue and patients' sociodemographic data and reflux-related symptoms and signs. Methods: Nasal biopsy samples were taken from 75 adult patients who underwent nasal surgery for chronic rhinosinusitis with polyposis (clinical group, n = 45) and a deviated septum (control group, n = 30). H pylori infection was identified using histochemical and rapid urease tests. Results: The prevalence of intranasal H pylori infection was significantly higher in the clinical group (28.9 per cent) compared to the control group (3.3 per cent) (p = 0.005). A significant yet weak association was found between positive H pylori status and laryngopharyngeal reflux related hypertrophy of the posterior commissure of the larynx. No other correlations reached statistical significance. Conclusion: H pylori infection is potentially related to chronic rhinosinusitis with polyposis. Further research is needed to clarify the role of H pylori as a risk factor for the development of sinonasal diseases and to examine its link with laryngopharyngeal reflux.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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