CT colonography: size reduction of submerged colorectal polyps due to electronic cleansing and CT-window settings.

Objectives: To assess whether electronic cleansing (EC) of tagged residue and different computed tomography (CT) windows influence the size of colorectal polyps in CT colonography (CTC).Methods: A database of 894 colonoscopy-validated CTC datasets of a low-prevalence cohort was retrospectively revie...

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Publicado en:European Radiology Vol. 28; no. 11; pp. 4766 - 4775
Autores principales: Bräuer, Christian, Lefere, Philippe, Gryspeerdt, Stefaan, Ringl, Helmut, Al-Mukhtar, Ali, Apfaltrer, Paul, Berzaczy, Dominik, Füger, Barbara, Furtner, Julia, Müller-Mang, Christina, Pones, Matthias, Scharitzer, Martina, Woitek, Ramona, Graser, Anno, Weber, Michael, Mang, Thomas
Formato: Journal Article
Publicado: Springer Nature Nov2018
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: CT colonography: size reduction of submerged colorectal polyps due to electronic cleansing and CT-window settings.
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          Bräuer, Christian
          Lefere, Philippe
          Gryspeerdt, Stefaan
          Ringl, Helmut
          Al-Mukhtar, Ali
          Apfaltrer, Paul
          Berzaczy, Dominik
          Füger, Barbara
          Furtner, Julia
          Müller-Mang, Christina
          Pones, Matthias
          Scharitzer, Martina
          Woitek, Ramona
          Graser, Anno
          Weber, Michael
          Mang, Thomas
        affil: Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria
      sug:
        subj:
          Colonic Polyps
          Colonography, Computed Tomographic Methods
          Image Processing, Computer Assisted Methods
          Analysis of Variance
          Retrospective Design
          Female
          Algorithms
          Middle Age
          Sensitivity and Specificity
          Aged
          Male
          Colonography, Computed Tomographic Standards
          Weights and Measures
          Middle Aged: 45-64 years
          Aged: 65+ years
          Female
          Male
      ab: Objectives: To assess whether electronic cleansing (EC) of tagged residue and different computed tomography (CT) windows influence the size of colorectal polyps in CT colonography (CTC).Methods: A database of 894 colonoscopy-validated CTC datasets of a low-prevalence cohort was retrospectively reviewed to identify patients with polyps ≥6 mm that were entirely submerged in tagged residue. Ten radiologists independently measured the largest diameter of each polyp, two-dimensionally, before and after EC in colon, bone, and soft-tissue-windows, in randomised order. Differences in size and polyp count before and after EC were calculated for size categories ≥6 mm and ≥10 mm. Statistical testing involved 95% confidence interval, intraclass correlation and mixed-model ANOVA.Results: Thirty-seven patients with 48 polyps were included. Mean polyp size before EC was 9.8 mm in colon, 9.9 mm in bone and 8.2 mm in soft-tissue windows. After EC, the mean polyp size decreased significantly to 9.4 mm in colon, 9.1 mm in bone and 7.1 mm in soft-tissue windows. Compared to unsubtracted colon windows, EC, performed in colon, bone and soft-tissue windows, led to a shift of 6 (12,5%), 10 (20.8%) and 25 (52.1%) polyps ≥6 mm into the next smaller size category, thus affecting patient risk stratification.Conclusions: EC and narrow CT windows significantly reduce the size of polyps submerged in tagged residue. Polyp measurements should be performed in unsubtracted colon windows.Key Points: • EC significantly reduces the size of polyps submerged in tagged residue. • Abdominal CT-window settings significantly underestimate 2D sizes of submerged polyps. • Size reduction in EC is significantly greater in narrow than wide windows. • Underestimation of polyp size due to EC may lead to inadequate treatment. • Polyp measurements should be performed in unsubtracted images using a colon window.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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