Somatotopic heat pain thresholds and intraepidermal nerve fibers in health.
Introduction: For sequential and somatotopic assessment of small fiber neuropathy, heat pain (HP) tests of hypoalgesia might be used instead of decreased counts of epidermal nerve fibers (ENFs), but then healthy subject reference values of HP thresholds are needed.Methods: Using the Computer Assiste...
| Publicado en: | Muscle & Nerve Vol. 58; no. 4; pp. 509 - 517 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Wiley-Blackwell
Oct2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=132203478&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 132203478 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0148639X 2S7 jtl: Muscle & Nerve issn: 0148639X maglogo: Y pubinfo: dt: Oct2018 vid: 58 iid: 4 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 132203478 132203478 NLM29543981 132203478 10.1002/mus.26128 NLM29543981 132203478 ppf: 509 ppct: 8 formats: tig: atl: Somatotopic heat pain thresholds and intraepidermal nerve fibers in health. aug: au: Davies, Jenny L. Engelstad, Sr.,, Janean K. E. Gove, Linde Linbo, Linda K. Carter, Rickey E. Lynch, Christopher Staff, Nathan P. Klein, Christopher J. Dyck, P. James B. Herrmann, David N. Dyck, Peter J. Engelstad, Janean K Sr., affil: Department of Neurology, Mayo Clinic, 200 First Street SW Rochester, Minnesota, USA, 55905 sug: subj: Epidermis Innervation Nerve Fibers Physiology Heat Pain Threshold Physiology Research Subjects Human Female Adolescence Male Aged Young Adult Middle Age Reference Values Epidermis Anatomy and Histology Aged, 80 and Over Adult Validation Studies Comparative Studies Evaluation Research Multicenter Studies Adolescent: 13-18 years Aged: 65+ years Middle Aged: 45-64 years Aged, 80 & over Adult: 19-44 years Female Male ab: Introduction: For sequential and somatotopic assessment of small fiber neuropathy, heat pain (HP) tests of hypoalgesia might be used instead of decreased counts of epidermal nerve fibers (ENFs), but then healthy subject reference values of HP thresholds are needed.Methods: Using the Computer Assisted Sensation Evaluator IVc system, HP thresholds of hypoalgesia were estimated for 10 unilateral sites and counts of ENFs for 4 of them in healthy subjects.Results: In healthy subjects, small but statistically significant differences of both HP thresholds of hypoalgesia and counts of ENFs were observed among tested sites. Significant correlations between HP thresholds and counts of ENFs were not found.Discussion: For the studied somatotopic sites, we provide ≥95th and ≥99th percentile reference limits for HP 0.5 and 5 of 1-10 HP thresholds of hypoalgesia and decreased counts of ENFs at ≤5th and ≤1st percentile levels. Muscle Nerve 58: 509-516, 2018. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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