The use of topical calcineurin inhibitors in chronic wound management.
The management of wounds has evolved over many years and with a greater understanding of the mechanisms of skin repair, a recent approach to treatment is to address the changes in tissue. Complex chronic wounds place a significant challenge on health professionals working with these patients, in acc...
| Publicado en: | Wound Practice & Research Vol. 26; no. 3; pp. 140 - 146 |
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| Autor principal: | |
| Formato: | case study pictorial research tables/charts Journal Article |
| Publicado: |
Cambridge Publishing
Sep2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=132213352&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 132213352 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18376304 639G jtl: Wound Practice & Research issn: 18376304 maglogo: N pubinfo: dt: Sep2018 vid: 26 iid: 3 pid: 66266 pub: Cambridge Publishing artinfo: ui: 132213352 132213352 132213352 132213352 ppf: 140 ppct: 6 formats: fmt: @attributes: type: P tig: atl: The use of topical calcineurin inhibitors in chronic wound management. aug: au: Sussman, G. affil: Associate Professor of Wound Care, Monash Institute for Health and Clinical Education, Faculty of Medicine, Nursing and Health Science, Monash University, VIC, Australia sug: subj: Tacrolimus Antagonists and Inhibitors Tacrolimus Therapeutic Use Hydrolases Antagonists and Inhibitors Hydrolases Therapeutic Use Administration, Topical Wounds, Chronic Drug Therapy Wound Care Human Wound Healing Bandages and Dressings Pyoderma Gangrenosum Diagnosis Lupus Erythematosus, Cutaneous Drug Therapy Middle Age Aged, 80 and Over Male Female Dermatitis, Atopic Drug Therapy Eczema Drug Therapy Tacrolimus Administration and Dosage Middle Aged: 45-64 years Aged, 80 & over Male Female ab: The management of wounds has evolved over many years and with a greater understanding of the mechanisms of skin repair, a recent approach to treatment is to address the changes in tissue. Complex chronic wounds place a significant challenge on health professionals working with these patients, in accurately identifying the underlying cause of the wound and the tissue factors impacting on wound healing. Many different types of dressings are used with limited success; however, dressings do not address the imbalances in tissue. Once a clear diagnosis has been established, the approach is to try to address this underlying imbalance in the tissues. Calcineurin inhibitors were approved for topical use in 2000-2001 for the treatment of atopic dermatitis. Since that time, their use has expanded to treat a number of chronic wounds, including pyoderma gangrenosum, cutaneous lupus erythematosus and other uncommon chronic wounds, with some success. This approach, in contrast to dressings that only impact on the wound environment, addresses the need to restore tissue balance and thus encourage wound healing. pubtype: Academic Journal doctype: case study pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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