Constitutive Interferon Pathway Activation in Tumors as an Efficacy Determinant Following Oncolytic Virotherapy.

Background: Attenuated measles virus (MV) strains are promising agents currently being tested against solid tumors or hematologic malignancies in ongoing phase I and II clinical trials; factors determining oncolytic virotherapy success remain poorly understood, however.Methods: We performed RNA sequ...

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Publicado en:	JNCI: Journal of the National Cancer Institute Vol. 110; no. 10; pp. 1123 - 1133
Autores principales:	Kurokawa, Cheyne, Iankov, Ianko D, Aderca, Ileana, Galanis, Evanthia, Anderson, S Keith, Leontovich, Alexey A, Maurer, Matthew J, Oberg, Ann L, Schroeder, Mark A, Sarkaria, Jann N, Giannini, Caterina, Jentoft, Mark E, Jen, Jin, Greiner, Suzanne M, Becker, Marc A, Haluska, Paul, Weroha, S John, Thompson, E Aubrey, Parney, Ian F
Formato:	research Journal Article
Publicado:	Oxford University Press / USA Oct2018
Acceso en línea:	Ver este registro en EBSCOhost