Impact of maternal pre‐pregnancy overweight on infant overweight at 1 year of age: associations and sex‐specific differences.
Summary: Background: Maternal overweight or obesity (OWOB) is linked to gestational diabetes, fetal macrosomia and higher rates of caesarean delivery. Objectives: The study aims to assess whether maternal pre‐pregnancy OWOB is associated with infant overweight in a sex‐dependent manner, independent...
| Publicado en: | Pediatric Obesity Vol. 13; no. 10; pp. 579 - 590 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Oct2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=132394265&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 132394265 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 20476302 ETV7 jtl: Pediatric Obesity issn: 20476302 maglogo: Y pubinfo: dt: Oct2018 vid: 13 iid: 10 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 132394265 132394265 132394265 10.1111/ijpo.12291 132394265 ppf: 579 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Impact of maternal pre‐pregnancy overweight on infant overweight at 1 year of age: associations and sex‐specific differences. aug: au: Bridgman, S. L. Azad, M. B. Persaud, R. R. Chari, R. S. Becker, A. B. Sears, M. R. Mandhane, P. J. Turvey, S. E. Subbarao, P. Haqq, A. M. Kozyrskyj, A. L. affil: Department of Pediatrics, University of Alberta, Edmonton AB, Canada sug: subj: Obesity Complications Pediatric Obesity Risk Factors Microbiota Maternal-Child Health Sex Factors Human Pregnancy Female Infant Prospective Studies Body Mass Index Age Factors Linear Regression Logistic Regression Delivery, Obstetric Breast Feeding Antibiotics Adverse Effects Male Infant: 1-23 months Female Male ab: Summary: Background: Maternal overweight or obesity (OWOB) is linked to gestational diabetes, fetal macrosomia and higher rates of caesarean delivery. Objectives: The study aims to assess whether maternal pre‐pregnancy OWOB is associated with infant overweight in a sex‐dependent manner, independent of microbiota‐altering variables. Methods: Weight and length measurements of 955 mother–infant pairs were obtained from the Canadian Healthy Infant Longitudinal Development cohort. Maternal pre‐pregnancy weight was defined as follows: normal, overweight (25 ≤ body mass index < 30) and obese (body mass index ≥ 30). Age and sex‐adjusted weight‐for‐length z‐scores >97th percentile were classified as infant overweight at age 1 year. Associations between pre‐pregnancy and infant overweight were determined by linear and logistic regression, adjusting for covariates. Results: Maternal pre‐pregnancy OWOB were associated with infant weight‐for‐length and overweight risk at 1 year. Except for pre‐pregnancy obesity, these associations were not attenuated appreciably after adjustment for birth mode, exclusivity of breastfeeding, exposure to antibiotics and infant sex. Yet only boys born to mothers with obesity were three times more likely to become overweight at age 1 independent of microbiota‐altering variables. Pre‐pregnancy obesity was associated with weight‐for‐length in male and female infants. Conclusions: Maternal pre‐pregnancy OWOB increases the risk of infant overweight, and this association is more evident in male infants. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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