Tumor Segmentation in Contrast-Enhanced Magnetic Resonance Imaging for Nasopharyngeal Carcinoma: Deep Learning with Convolutional Neural Network.

Objectives. To evaluate the application of a deep learning architecture, based on the convolutional neural network (CNN) technique, to perform automatic tumor segmentation of magnetic resonance imaging (MRI) for nasopharyngeal carcinoma (NPC). Materials and Methods. In this prospective study, 87 MRI...

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Publicado en:BioMed Research International pp. 1 - 8
Autores principales: Li, Qiaoliang, Xu, Yuzhen, Chen, Zhewei, Liu, Dexiang, Feng, Shi-Ting, Law, Martin, Ye, Yufeng, Huang, Bingsheng
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Wiley-Blackwell 10/17/2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 10/17/2018
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2018/9128527
        132445964
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        atl: Tumor Segmentation in Contrast-Enhanced Magnetic Resonance Imaging for Nasopharyngeal Carcinoma: Deep Learning with Convolutional Neural Network.
      aug:
        au:
          Li, Qiaoliang
          Xu, Yuzhen
          Chen, Zhewei
          Liu, Dexiang
          Feng, Shi-Ting
          Law, Martin
          Ye, Yufeng
          Huang, Bingsheng
        affil: School of Biomedical Engineering, Health Science Centre, Shenzhen University, Shenzhen, China
      sug:
        subj:
          Contrast Media Diagnostic Use
          Magnetic Resonance Imaging Methods
          Neural Networks (Computer)
          Nasopharyngeal Neoplasms Radiography
          Human
          Prospective Studies
          China
      ab: Objectives. To evaluate the application of a deep learning architecture, based on the convolutional neural network (CNN) technique, to perform automatic tumor segmentation of magnetic resonance imaging (MRI) for nasopharyngeal carcinoma (NPC). Materials and Methods. In this prospective study, 87 MRI containing tumor regions were acquired from newly diagnosed NPC patients. These 87 MRI were augmented to >60,000 images. The proposed CNN network is composed of two phases: feature representation and scores map reconstruction. We designed a stepwise scheme to train our CNN network. To evaluate the performance of our method, we used case-by-case leave-one-out cross-validation (LOOCV). The ground truth of tumor contouring was acquired by the consensus of two experienced radiologists. Results. The mean values of dice similarity coefficient, percent match, and their corresponding ratio with our method were 0.89±0.05, 0.90±0.04, and 0.84±0.06, respectively, all of which were better than reported values in the similar studies. Conclusions. We successfully established a segmentation method for NPC based on deep learning in contrast-enhanced magnetic resonance imaging. Further clinical trials with dedicated algorithms are warranted.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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