Sonoelastography for the Assessment of Muscle Changes in Amyotrophic Lateral Sclerosis: Results of a Pilot Study.

The purpose of this study was to assess the sonoelastographic features of four different muscles in patients with amyotrophic lateral sclerosis compared with healthy controls and to evaluate the relationship of these features to muscle strength and other ultrasonographic variables. Fourteen patients...

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Publicado en:Ultrasound in Medicine & Biology Vol. 44; no. 12; pp. 2540 - 2548
Autores principales: Martínez-Payá, Jacinto J., Del Baño-Aledo, María Elena, Ríos-Díaz, José, Fornés-Ferrer, Victoria, Vázquez-Costa, Juan F.
Formato: Journal Article
Publicado: Elsevier B.V. Dec2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2018
      vid: 44
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      pub: Elsevier B.V.
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        10.1016/j.ultrasmedbio.2018.08.009
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        atl: Sonoelastography for the Assessment of Muscle Changes in Amyotrophic Lateral Sclerosis: Results of a Pilot Study.
      aug:
        au:
          Martínez-Payá, Jacinto J.
          Del Baño-Aledo, María Elena
          Ríos-Díaz, José
          Fornés-Ferrer, Victoria
          Vázquez-Costa, Juan F.
        affil: ECOFISTEM Research Group, Health Sciences Department, Facultad de Ciencias de la Salud, Universidad Católica de Murcia, Guadalupe (Murcia), Spain
      sug:
        subj:
          Amyotrophic Lateral Sclerosis Complications
          Ultrasonography Methods
          Muscular Atrophy Etiology
          Muscular Atrophy
          Image Processing, Computer Assisted Methods
          Muscle, Skeletal Physiopathology
          Middle Age
          Pilot Studies
          Muscle Strength Physiology
          Muscular Atrophy Physiopathology
          Muscle, Skeletal
          Male
          Female
          Middle Aged: 45-64 years
          Male
          Female
      ab: The purpose of this study was to assess the sonoelastographic features of four different muscles in patients with amyotrophic lateral sclerosis compared with healthy controls and to evaluate the relationship of these features to muscle strength and other ultrasonographic variables. Fourteen patients with amyotrophic lateral sclerosis and 20 controls were examined using strain sonoelastography scanning. The RGB channel fraction ratio was analyzed with ImageJ software (Version 1.48). Two main sonoelastographic patterns could be distinguished in the controls: a clear predominance of the blue channel (hard areas) and a more heterogeneous pattern with predominance of the green channel (intermediate stiffness). These patterns were also observed in patients, although a higher green channel score was observed in mildly impaired muscles, whereas a higher blue channel score was observed in the most severely impaired muscle. Sonoelastography may be a good complementary biomarker in the detection and monitoring of muscle changes in amyotrophic lateral sclerosis.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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