Understanding pyoderma gangrenosum.

Pyoderma gangrenosum (PG) is a rare immune-related chronic ulcerating skin condition with a predilection for the lower limbs. It is more common in females, with the average age of onset between 20 and 50 years. There are two stages of the disease process: an ulcerative phase and a healing phase. The...

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Publicado en:Wounds UK Vol. 14; no. 5; pp. 87 - 92
Autor principal: YOUNG, TRUDIE
Formato: pictorial review Journal Article
Publicado: SB Communications Group, A Schofield Media Company 2018
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Understanding pyoderma gangrenosum.
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        au: YOUNG, TRUDIE
        affil: Director of Education and Training, Welsh Wound Innovation Centre, Ynysmaerdy, Rhondda Cynon Taff, Wales
      sug:
        subj:
          Pyoderma Gangrenosum
          Pyoderma Gangrenosum Epidemiology
          Pyoderma Gangrenosum Physiopathology
          Pyoderma Gangrenosum Symptoms
          Pyoderma Gangrenosum Diagnosis
          Pyoderma Gangrenosum Risk Factors
          Pyoderma Gangrenosum Classification
          Pyoderma Gangrenosum Therapy
          Wound Care
          Bandages and Dressings
      ab: Pyoderma gangrenosum (PG) is a rare immune-related chronic ulcerating skin condition with a predilection for the lower limbs. It is more common in females, with the average age of onset between 20 and 50 years. There are two stages of the disease process: an ulcerative phase and a healing phase. The latter occurs once the heightened and ongoing inflammatory response has subsided, although the exact pathophysiology of PG has yet to be elucidated. Half of the cases of PG are associated with other comorbidities, such as inflammatory bowel disease, arthritis or haematological malignancies. The skin condition pathergy can be a stimulus for the onset of the disease and is due to incidental or healthcare-related trauma. There is no definitive test to diagnose PG and the diagnosis is one of exclusion. The aim of the treatment is to reduce the inflammation and therefore immunosuppression is the basis of any therapy. Nevertheless, the disease can recur following completion of the healing phase.
      pubtype: Academic Journal
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        pictorial
        review
        Journal Article
      ougenre: Article
    language: English
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