The impact of age on cardiac electromechanical function in asymptomatic individuals.
Background and Aim: Whether aging affects left ventricular (LV) filling and ejection and the LV electric function is not well established. We investigated the effect of normal aging on echocardiographic measurements of LV morphology and function, LV electric function and the relationship between LV...
| Publicado en: | Echocardiography Vol. 35; no. 11; pp. 1788 - 1795 |
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| Autores principales: | , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Nov2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=132851832&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 132851832 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 07422822 GSE jtl: Echocardiography issn: 07422822 maglogo: Y pubinfo: dt: Nov2018 vid: 35 iid: 11 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 132851832 132851832 132851832 10.1111/echo.14145 132851832 ppf: 1788 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: The impact of age on cardiac electromechanical function in asymptomatic individuals. aug: au: Vancheri, Federico Henein, Michael affil: Internal Medicine, Ospedale S. Elia, Caltanissetta Italy sug: subj: Cardiovascular System Physiology Aging Echocardiography Methods Heart Ventricle, Left Physiology Ventricular Ejection Fraction Human Cross Sectional Studies Surveys Prevalence Italy Coronary Disease Risk Factors Coronary Arteriosclerosis Symptoms Heart Failure Symptoms Electrocardiography Methods QRS Complex Automation Systolic Pressure Diastolic Pressure Ultrasonography, Doppler Methods Heart Atrium, Left Physiology Biological Markers ab: Background and Aim: Whether aging affects left ventricular (LV) filling and ejection and the LV electric function is not well established. We investigated the effect of normal aging on echocardiographic measurements of LV morphology and function, LV electric function and the relationship between LV electric and mechanical function in asymptomatic individuals. Methods: As part of a cross‐sectional survey for the prevalence of coronary risk factors in the general population in Caltanissetta, Italy, individuals without signs or symptoms of coronary artery disease or heart failure were randomly selected and underwent electrocardiographic and echocardiographic examination. QRS duration and amplitude, PR, QT and QTc intervals, were automatically measured. Echocardiographic examination included the measurement of LV systolic and diastolic dimensions, volumes and ejection fraction (EF). From the spectral Doppler flow LV early diastolic (E wave) and atrial systolic (A wave) velocities, isovolumic relaxation time (IVRT) and isovolumic contraction time (IVCT) were measured. Global LV dyssynchrony was assessed using the total isovolumic time (T‐IVT) and the Tei index. Results: Aging reduced LV long‐axis function, LV filling time and E wave velocity and prolonged T‐IVT, IVRT and Tei index. It did not affect LV dimensions, ejection fraction, IVCT or QRS amplitude and duration. QRS duration correlated with LV dimensions, wall thickness and left atrial area. QRS amplitude and QTc interval correlated with the markers of LV dyssynchrony T‐IVT and Tei index. Conclusions: Overall, systolic and electric LV function are not affected by age, whereas subendocardial function, diastolic and synchronous function are significantly influenced. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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