Epidemiology of pyoderma gangrenosum: Results from an Italian prospective multicentre study.

Pyoderma gangrenosum (PG) is a neutrophilic dermatosis characterised by painful, necrotic ulcerations. PG is described as a rare disease: the world‐wide incidence is estimated to be around 3 to 10 cases per million population per year. These estimations are based mostly on case reports and retrospec...

Descripción completa

Detalles Bibliográficos
Publicado en:International Wound Journal Vol. 15; no. 6; pp. 875 - 880
Autores principales: Monari, Paola, Moro, Ruggero, Motolese, Alberico, Misciali, Cosimo, Baraldi, Carlotta, Fanti, Pier Alessandro, Caccavale, Stefano, Puviani, Mario, Olezzi, Daniela, Zampieri, Pierfrancesco, Trevisan, Giusto, Nan, Katiuscia, Fiorentini, Chiara, Pellacani, Giovanni, Gualdi, Giulio
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Dec2018
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=132914231&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 132914231
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        17424801
        1725
      jtl: International Wound Journal
      issn: 17424801
      maglogo: Y
    pubinfo:
      dt: Dec2018
      vid: 15
      iid: 6
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
    artinfo:
      ui:
        132914231
        132914231
        132914231
        10.1111/iwj.12939
        132914231
      ppf: 875
      ppct: 5
      formats:
      tig:
        atl: Epidemiology of pyoderma gangrenosum: Results from an Italian prospective multicentre study.
      aug:
        au:
          Monari, Paola
          Moro, Ruggero
          Motolese, Alberico
          Misciali, Cosimo
          Baraldi, Carlotta
          Fanti, Pier Alessandro
          Caccavale, Stefano
          Puviani, Mario
          Olezzi, Daniela
          Zampieri, Pierfrancesco
          Trevisan, Giusto
          Nan, Katiuscia
          Fiorentini, Chiara
          Pellacani, Giovanni
          Gualdi, Giulio
        affil: Department of Dermatology, ASST degli Spedali Civili, Spedali Civili di Brescia, Brescia Italy
      sug:
        subj:
          Pyoderma Gangrenosum Epidemiology
          Human
          Italy
          Prospective Studies
          Multicenter Studies
          Pyoderma Gangrenosum Diagnosis
          Dermatology
          Incidence
          Nonexperimental Studies
      ab: Pyoderma gangrenosum (PG) is a neutrophilic dermatosis characterised by painful, necrotic ulcerations. PG is described as a rare disease: the world‐wide incidence is estimated to be around 3 to 10 cases per million population per year. These estimations are based mostly on case reports and retrospective case series; there are no prospective, multicentre studies on the matter. The apparent rarity of PG is in contrast with our clinical perception as dermatologists: in our opinion, PG is not so uncommon. Therefore, we decide to investigate the epidemiology of PG in the Italian population and confirm our clinical suspicions that it is not an orphan disease. We enrolled all patients diagnosed with PG in 8 Italian Dermatological Departments from 1st October 2014 to 1st November 2015, and we recorded their features. Our data, collected from 64 patients, are in accordance with those of the published literature regarding the epidemiology and features of PG. In an Italian population of roughly 8 million inhabitants of 7 provinces, we found an incidence of 5.17 new cases per million population per year. Unlike our predictions before the study, we confirmed the world‐wide incidence of PG. To our knowledge, this is the first observational, multicentre study on PG. We hope that it provides a stimulus for further researches on PG and for the creation of an Italian register.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N