Effect of Inorganic Nitrite vs Placebo on Exercise Capacity Among Patients With Heart Failure With Preserved Ejection Fraction: The INDIE-HFpEF Randomized Clinical Trial.

Importance: There are few effective treatments for heart failure with preserved ejection fraction (HFpEF). Short-term administration of inorganic nitrite or nitrate preparations has been shown to enhance nitric oxide signaling, which may improve aerobic capacity in HFpEF.Objective: To determine the...

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Bibliographic Details

Published in:	JAMA: Journal of the American Medical Association Vol. 320; no. 17; pp. 1764 - 1774
Main Authors:	Borlaug, Barry A., Anstrom, Kevin J., Lewis, Gregory D., Shah, Sanjiv J., Levine, James A., Koepp, Gabe A., Givertz, Michael M., Felker, G. Michael, LeWinter, Martin M., Mann, Douglas L., Margulies, Kenneth B., Smith, Andrew L., Tang, W. H. Wilson, Whellan, David J., Chen, Horng H., Davila-Roman, Victor G., McNulty, Steven, Desvigne-Nickens, Patrice, Hernandez, Adrian F., Braunwald, Eugene
Format:	research randomized controlled trial Journal Article
Published:	American Medical Association 11/6/2018
Online Access:	View this record in EBSCOhost