Intelligence Algorithms for Protein Classification by Mass Spectrometry.

Mass spectrometry (MS) is an important technique in protein research. Effective classification methods by MS data could contribute to early and less-invasive diagnosis and also facilitate developments in the bioinformatics field. As MS data is featured by high dimension, appropriate methods which ca...

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Published in:BioMed Research International pp. 1 - 12
Main Authors: Fan, Zichuan, Kong, Fanchen, Zhou, Yang, Chen, Yiqing, Dai, Yalan
Format: review tables/charts Journal Article
Published: Wiley-Blackwell 11/11/2018
Online Access:View this record in EBSCOhost
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      dt: 11/11/2018
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2018/2862458
        132934824
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        atl: Intelligence Algorithms for Protein Classification by Mass Spectrometry.
      aug:
        au:
          Fan, Zichuan
          Kong, Fanchen
          Zhou, Yang
          Chen, Yiqing
          Dai, Yalan
        affil: School of Computer and Information Science, Southwest University, Chongqing 400715, China
      sug:
        subj:
          Proteins Classification
          Mass Spectrometry Methods
          Algorithms
          Bioinformatics
          Biological Markers
          Machine Learning
      ab: Mass spectrometry (MS) is an important technique in protein research. Effective classification methods by MS data could contribute to early and less-invasive diagnosis and also facilitate developments in the bioinformatics field. As MS data is featured by high dimension, appropriate methods which can effectively deal with the large amount of MS data have been widely studied. In this paper, the applications of methods based on intelligence algorithms have been investigated. Firstly, classification and biomarker analysis methods using typical machine learning approaches have been discussed. Then those are followed by the Ensemble strategy algorithms. Clearly, simple and basic machine learning algorithms hardly addressed the various needs of protein MS classification. Preprocessing algorithms have been also studied, as these methods are useful for feature selection or feature extraction to improve classification performance. Protein MS data growing with data volume becomes complicated and large; improvements in classification methods in terms of classifier selection and combinations of different algorithms and preprocessing algorithms are more emphasized in further work.
      pubtype: Academic Journal
      doctype:
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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