Utilizing soft constraints to enhance medical relation extraction from the history of present illness in electronic medical records.

Relation extraction between medical concepts from electronic medical records has pervasive applications as well as significance. However, previous researches utilizing machine learning algorithms judge the semantic types of medical concept pair mentions independently. In fact, different concept pair...

Descripción completa

Detalles Bibliográficos
Publicado en:Journal of Biomedical Informatics Vol. 87; pp. 108 - 118
Autores principales: Chen, Li, Li, Yuanju, Chen, Weipeng, Liu, Xinglong, Yu, Zhonghua, Zhang, Siyuan
Formato: research Journal Article
Publicado: Academic Press Inc. Nov2018
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=132992896&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 132992896
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        15320464
        OMB
      jtl: Journal of Biomedical Informatics
      issn: 15320464
      maglogo: N
    pubinfo:
      dt: Nov2018
      vid: 87
      pid: 735
      pub: Academic Press Inc.
      place: Burlington, Massachusetts
    artinfo:
      ui:
        132992896
        132992896
        NLM30292854
        132992896
        10.1016/j.jbi.2018.09.013
        NLM30292854
        132992896
      ppf: 108
      ppct: 10
      formats:
      tig:
        atl: Utilizing soft constraints to enhance medical relation extraction from the history of present illness in electronic medical records.
      aug:
        au:
          Chen, Li
          Li, Yuanju
          Chen, Weipeng
          Liu, Xinglong
          Yu, Zhonghua
          Zhang, Siyuan
        affil: Department of Computer Science, Sichuan University, Chengdu, China
      sug:
        subj:
          Medical Informatics Methods
          Probability
          Reproducibility of Results
          Regression
          Models, Statistical
          Human
          Algorithms
          China
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Clinical Assessment Tools
      ab: Relation extraction between medical concepts from electronic medical records has pervasive applications as well as significance. However, previous researches utilizing machine learning algorithms judge the semantic types of medical concept pair mentions independently. In fact, different concept pair mentions in the same context are of dependencies which can provide beneficial evidences for identifying their relation types. To the best of our knowledge, only one study has considered such dependencies in discharge summaries. However, its hard constraints are not applied effectively to the History of Present Illness (HPI) in electronic Medical Records. According to the writing characteristics of HPI records, we generalize two regularities of dependencies among concept pairs mentioned in an HPI record to enhance the performance of relation extraction. We incorporate the two soft constraints corresponding to the regularities and the posterior probabilities returned by a local classifier into a joint inference process which applies Integer Quadratic Programming method to carry out collective classification for all concept pair mentions in an HPI record. We implement four local classification models including support vector machine, logistics regression, random forest and piecewise convolutional neural networks to examine the performance of our approach. A series of experimental results demonstrate that our collective classification method has made a principal improvement and outperforms the other state-of-the-art methods.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N