Enhancement of low-quality fetal electrocardiogram based on time-sequenced adaptive filtering.

Extraction of a clean fetal electrocardiogram (ECG) from non-invasive abdominal recordings is one of the biggest challenges in fetal monitoring. An ECG allows for the interpretation of the electrical heart activity beyond the heart rate and heart rate variability. However, the low signal quality of...

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Publicado en:Medical & Biological Engineering & Computing Vol. 56; no. 12; pp. 2313 - 2324
Autores principales: Fotiadou, E., van Laar, J. O. E. H., Oei, S. G., Vullings, R.
Formato: Journal Article
Publicado: Springer Nature Dec2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2018
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s11517-018-1862-8
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        atl: Enhancement of low-quality fetal electrocardiogram based on time-sequenced adaptive filtering.
      aug:
        au:
          Fotiadou, E.
          van Laar, J. O. E. H.
          Oei, S. G.
          Vullings, R.
        affil: Department of Electrical Engineering, Eindhoven University of Technology, 5612 AP, Eindhoven, Netherlands
      sug:
        subj:
          Electrocardiography Methods
          Prenatal Diagnosis Methods
          Signal Processing, Computer Assisted
          Female
          Algorithms
          Sensitivity and Specificity
          Pregnancy
          Ferrans and Powers Quality of Life Index
          Questionnaires
          Scales
          Female
      ab: Extraction of a clean fetal electrocardiogram (ECG) from non-invasive abdominal recordings is one of the biggest challenges in fetal monitoring. An ECG allows for the interpretation of the electrical heart activity beyond the heart rate and heart rate variability. However, the low signal quality of the fetal ECG hinders the morphological analysis of its waveform in clinical practice. The time-sequenced adaptive filter has been proposed for performing optimal time-varying filtering of non-stationary signals having a recurring statistical character. In our study, the time-sequenced adaptive filter is applied to enhance the quality of multichannel fetal ECG after the maternal ECG is removed. To improve the performance of the filter in cases of low signal-to-noise ratio (SNR), we enhance the ECG reference signals by averaging consecutive ECG complexes. The performance of the proposed augmented time-sequenced adaptive filter is evaluated in both synthetic and real data from PhysioNet. This evaluation shows that the suggested algorithm clearly outperforms other ECG enhancement methods, in terms of uncovering the ECG waveform, even in cases with very low SNR. With the presented method, quality of the fetal ECG morphology can be enhanced to the extent that the ECG might be fit for use in clinical diagnostics. Graphical abstract The extracted fetal ECG signals from non-invasive abdominal recordings still contain a substantial amount of noise. The time-sequenced adaptive filter provides a relatively accurate estimate of the underlying fetal ECG signal when the quality of the reference channels is enhanced prior to filtering.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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