EIT Imaging of Intracranial Hemorrhage in Rabbit Models Is Influenced by the Intactness of Cranium.
Electrical impedance tomography (EIT) has been shown to be a promising, bedside imaging method to monitor the progression of intracranial hemorrhage (ICH). However, the observed impedance changes within brain related to ICH differed among groups, and we hypothesized that the cranium intactness (open...
| Publicado en: | BioMed Research International pp. 1 - 11 |
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| Autores principales: | , , , , , , , , |
| Formato: | equations & formulas pictorial research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
11/19/2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=133083289&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 133083289 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 11/19/2018 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 133083289 133083289 133083289 10.1155/2018/1321862 133083289 ppf: 1 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: EIT Imaging of Intracranial Hemorrhage in Rabbit Models Is Influenced by the Intactness of Cranium. aug: au: Dai, Meng Liu, Xue-Chao Li, Hao-Ting Xu, Can-Hua Yang, Bin Wang, Hang Shi, Xue-Tao Dong, Xiu-Zhen Fu, Feng affil: School of Biomedical Engineering, Air Force Military Medical University, Xi’an, China sug: subj: Intracranial Hemorrhage Diagnosis Electric Impedance Methods Skull Anatomy and Histology Animal Studies Rabbits Blood Transfusion, Autologous ab: Electrical impedance tomography (EIT) has been shown to be a promising, bedside imaging method to monitor the progression of intracranial hemorrhage (ICH). However, the observed impedance changes within brain related to ICH differed among groups, and we hypothesized that the cranium intactness (open or closed) may be the one of potential reasons leading to the difference. Therefore, the aim of this study was to investigate this effect of open or closed cranium on impedance changes within brain in the rabbit ICH model. In this study, we first established the ICH model in 12 rabbits with the open cranium and in 12 rabbits with the closed cranium. Simultaneously, EIT measurements on the rabbits’ heads were performed to record the impedance changes caused by injecting the autologous nonheparinized blood into cerebral parenchyma. Finally, the regional impedance changes on EIT images and the whole impedance changes were analyzed. It was surprisingly found that when the cranium was open, the impedance of the area where the blood was injected, as well as the whole brain impedance, decreased with the amount of blood being injected; when the cranium was closed, while the impedance of the area where blood was not injected continued to increase, the impedance of the area where blood was injected decreased within 20s of the blood being injected and then remained almost unchanged, and the whole brain impedance had a small fall and then notably increased. The results have validated that the cranium completeness (open or closed) has influences on impedance changes within brain when using EIT to monitor ICH. In future study on application of EIT to monitor ICH, the cranium completeness should be taken into account for establishing an ICH model and analyzing the corresponding EIT results. pubtype: Academic Journal doctype: equations & formulas pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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