Gender Identity and Sexual Function in 46,XX Patients with Congenital Adrenal Hyperplasia Raised as Males.
In individuals with congenital adrenal hyperplasia (CAH) and 46,XX karyotype, androgens produced by the adrenal glands during the intrauterine development promote virilization of the genitals, which may even result in the development of a well-formed penis. Some of these children with late diagnosis...
| Published in: | Archives of Sexual Behavior Vol. 47; no. 8; pp. 2491 - 2497 |
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| Main Authors: | , , , , , , , |
| Format: | journal article |
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Springer Nature
Nov2018
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| Subjects: | |
| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=133105945&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 133105945 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00040002 ASX jtl: Archives of Sexual Behavior issn: 00040002 maglogo: N pubinfo: dt: Nov2018 vid: 47 iid: 8 pid: 237 pub: Springer Nature artinfo: ui: 133105945 10.1007/s10508-018-1299-z ppf: 2491 ppct: 6 formats: fmt: – @attributes: type: T – @attributes: type: P size: 854KB tig: atl: Gender Identity and Sexual Function in 46,XX Patients with Congenital Adrenal Hyperplasia Raised as Males. aug: au: Apóstolos, Robson A. C. Canguçu-Campinho, Ana Karina Lago, Renata Costa, Ana Carolina S. Oliveira, Luciana M. B. Toralles, Maria Betania Barroso, Ubirajara Barroso, Ubirajara Jr affil: Disorders of Sexual Development Clinic, Federal University of Bahia, Av Alphaville 1, Rua Pajuçara, 335, 41701015, Salvador, Bahia, Brazil Bahiana School of Medicine and Public Health, Salvador, Bahia, Brazil Disorders of Sexual Development Clinic, Federal University of Bahia, Av Alphaville 1, Rua Pajuçara, 335, Salvador, Bahia, 41701015, Brazil su: Intersexuality Gender identity Intersexual identity Human sexuality Genitalia Human reproduction Adrenogenital syndrome Hyperandrogenism Androgens Evaluation research Adrenal diseases Virilism Animal reproduction Research methodology Research Comparative studies Penile erection Disease complications sug: subj: Intersexuality Gender identity Intersexual identity Human sexuality Genitalia Human reproduction Adrenogenital syndrome Hyperandrogenism Androgens Evaluation research Adrenal diseases Virilism Animal reproduction Research methodology Research Comparative studies Penile erection Disease complications keyword: Congenital adrenal hyperplasia Disorders of sex development Intersex Congenital adrenal hyperplasia Disorders of sex development Intersex ab: In individuals with congenital adrenal hyperplasia (CAH) and 46,XX karyotype, androgens produced by the adrenal glands during the intrauterine development promote virilization of the genitals, which may even result in the development of a well-formed penis. Some of these children with late diagnosis are registered as males after birth. After obtaining approval from the internal review board, we evaluated gender identity and sexual function in four 46,XX severely virilized patients with CAH, who were originally registered and raised as males, assisted in our Disorders of Sexual Development Clinic. The evaluation consisted of questionnaires to assess gender identity and sexual activity and interview with the multidisciplinary team that provides care for these patients. The patients underwent surgery to remove uterus, ovaries, and remaining vaginal structures, in addition to implantation of testicular prosthesis and correction of hypospadias, when necessary. All four patients have developed a clear male gender identity, and when evaluated for sexual activity, they have reported having erections, libido, orgasms, and sexual attraction to women only. Two of these 4 patients had satisfactory sexual intercourses when assessed using the International Index of Erectile Function questionnaire. The other two patients who never had sexual intercourse reported not having a partner for sexual activity; one is 18 years old, and the other is 14 years old. This study showed that this group of 46,XX severely virilized patients with CAH, registered and raised as males, adapted well to the assigned male gender, with satisfactory sexual function in patients who had sexual intercourse. pubtype: Academic Journal doctype: journal article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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