Attention and executive functions computer training for attention-deficit/hyperactivity disorder (ADHD): results from a randomized, controlled trial.

Multicenter randomized clinical superiority single-blind trial investigated the effect of a computer training program targeting multiple cognitive functions. Seventy children with ADHD, aged 6-13, were randomized to intervention or control group. The intervention group used ACTIVATE™ for 8 weeks and...

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Published in:European Child & Adolescent Psychiatry Vol. 27; no. 12; pp. 1563 - 1575
Main Authors: Bikic, Aida, Leckman, James F., Christensen, Torben Ø., Bilenberg, Niels, Dalsgaard, Søren
Format: research tables/charts randomized controlled trial Journal Article
Published: Springer Nature Dec2018
Online Access:View this record in EBSCOhost
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      place: New York, New York
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        atl: Attention and executive functions computer training for attention-deficit/hyperactivity disorder (ADHD): results from a randomized, controlled trial.
      aug:
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          Bikic, Aida
          Leckman, James F.
          Christensen, Torben Ø.
          Bilenberg, Niels
          Dalsgaard, Søren
        affil: Department of Child and Adolescent Mental Health Services Southern Jutland, Region of Southern Denmark, Kresten Phillipsens Vej 15, Aabenraa, Denmark
      sug:
        subj:
          Attention Education
          Executive Function Education
          Computer-Assisted Instruction In Infancy and Childhood
          Attention Deficit Hyperactivity Disorder Therapy
          Human
          Randomized Controlled Trials
          Single-Blind Studies
          Child
          Adolescence
          Behavioral Symptoms
          Functional Assessment
          Confidence Intervals
          Parental Attitudes
          Teachers Psychosocial Factors
          Scales
          Multicenter Studies
          Outcomes of Education
          Child: 6-12 years
          Adolescent: 13-18 years
      ab: Multicenter randomized clinical superiority single-blind trial investigated the effect of a computer training program targeting multiple cognitive functions. Seventy children with ADHD, aged 6-13, were randomized to intervention or control group. The intervention group used ACTIVATE™ for 8 weeks and both groups received treatment as usual and were assessed in regard to cognitive functions, symptoms, behavioral and functional outcome measures after 8, 12 and 24 weeks. There was no significant effect on the primary outcome, sustained attention (β = − 0.047; CI − 0.247 to 0.153) or the secondary outcomes [parent-rated ADHD-RS, β = − 0.037; CI (− 0.224 to 0.150); teacher-rated-ADHD-RS, β = 0.093; CI (− 0.107 to 0.294); parent-rated-BRIEF, β = − 0.119; CI (− 0.307 to 0.069); and teacher-rated-BRIEF, β = 0.136; CI (− 0.048 to 0.322)]. This multicenter randomized clinical trial found no significant beneficial effects of cognitive training using the computer program ACTIVATE on the primary or secondary outcome measures in children with ADHD. Nevertheless, our study was likely underpowered to detect small to moderate changes.Trial registration ClinicalTrials.gov: NCT01752530, date of registration: December 10, 2012.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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