Automated ASPECT rating: comparison between the Frontier ASPECT Score software and the Brainomix software.

Purpose: Computer-aided diagnosis (CAD) appears promising in early ischemic change detection computed tomography (CT). This study aimed to compare the performance of two new CAD systems (Frontier ASPECTS Prototype and Brainomix) with two experienced readers in selected patients with suspected acute...

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Published in:Neuroradiology Vol. 60; no. 12; pp. 1267 - 1273
Main Authors: Goebel, Juliane, Stenzel, Elena, Guberina, Nika, Wanke, Isabel, Koehrmann, Martin, Kleinschnitz, Christoph, Umutlu, Lale, Forsting, Michael, Moenninghoff, Christoph, Radbruch, Alexander
Format: diagnostic images research tables/charts Journal Article
Published: Springer Nature Dec2018
Online Access:View this record in EBSCOhost
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      dt: Dec2018
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00234-018-2098-x
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        atl: Automated ASPECT rating: comparison between the Frontier ASPECT Score software and the Brainomix software.
      aug:
        au:
          Goebel, Juliane
          Stenzel, Elena
          Guberina, Nika
          Wanke, Isabel
          Koehrmann, Martin
          Kleinschnitz, Christoph
          Umutlu, Lale
          Forsting, Michael
          Moenninghoff, Christoph
          Radbruch, Alexander
        affil: Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany
      sug:
        subj:
          Diagnosis, Computer Assisted
          Software
          Ischemia Diagnosis
          Stroke Diagnosis
          Automation
          Human
          Retrospective Design
          Middle Cerebral Artery Pathology
          Middle Cerebral Artery Radiography
          Computed Tomography Angiography
          Intraclass Correlation Coefficient
          Radiologists
          Descriptive Statistics
      ab: Purpose: Computer-aided diagnosis (CAD) appears promising in early ischemic change detection computed tomography (CT). This study aimed to compare the performance of two new CAD systems (Frontier ASPECTS Prototype and Brainomix) with two experienced readers in selected patients with suspected acute ischemic stroke.Methods: Retrospectively, non-contrast brain CTs of 150 patients suspected for acute middle cerebral artery ischemia were analyzed with respect to ASPECTS first separately, than in consensus by two senior radiologists, and by use of Frontier and Brainomix. Besides the fully automatic Frontier and Brainomix readings (Frontier_1, Brainomix_1), readings adjusted for the affected brain side (known by CT angiography or clinical presentation, Frontier_2, Brainomix_2) were assessed. Statistical analysis was performed by intraclass correlation and Bland-Altman statistics.Results: The score-based ASPECTS readings of Brainomix_1, Brainomix_2, both radiologists, and the expert consensus reading correlated highly (r = 0.714 to 0.841; always p < 0.001), whereas Frontier_1 and Frontier_2 correlated only lowly or moderately with both radiologists, the expert consensus reading, and Brainomix (r = 0.471 to 0.680; always p < 0.001). Bland-Altman analysis revealed lower mean ASPECT difference and standard deviation of difference for Brainomix_2 (mean difference = −0.2; SD = 1.15) compared to Frontier_2 (mean difference = 1.2; SD = 1.76). Correlation of region-based ASPECTS reading with the expert consensus reading was moderate for Brainomix_2 (r = 0.534), but only low for Frontier_2 (r = 0283; always p < 0.001).Conclusion: We found high agreement in ASPECTS rating between both radiologists, expert consensus reading, and Brainomix, but only low to moderate agreement to Frontier.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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