Anti-Helicobacter pylori Potential of Three Edible Plants Known as Quelites in Mexico.

"Quelites" are edible plants that are part of the traditional agro-ecosystems in Mexico. These plants, despite their already known nutritional properties, are now considered neglected and underutilized species. With the objective of promoting their reinsertion in the markets and mainly, in daily die...

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Publicado en:Journal of Medicinal Food Vol. 21; no. 11; pp. 1150 - 1158
Autores principales: Gomez-Chang, Erika, Uribe-Estanislao, Guadalupe Vanessa, Martinez-Martinez, Maricruz, Gálvez-Mariscal, Amanda, Romero, Irma
Formato: research tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. Nov2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2018
      vid: 21
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      pub: Mary Ann Liebert, Inc.
      place: New Rochelle, New York
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        10.1089/jmf.2017.0137
        133112055
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        atl: Anti-Helicobacter pylori Potential of Three Edible Plants Known as Quelites in Mexico.
      aug:
        au:
          Gomez-Chang, Erika
          Uribe-Estanislao, Guadalupe Vanessa
          Martinez-Martinez, Maricruz
          Gálvez-Mariscal, Amanda
          Romero, Irma
        affil: Department of Biochemistry, Faculty of Medicine, Universidad Nacional Autónoma de México, Ciudad Universitaria, Cd. Mx., México.
      sug:
        subj:
          Plants, Edible Pharmacodynamics
          Spinach Pharmacodynamics
          Helicobacter Pylori Drug Effects
          Mexico
          Helicobacter Infections Complications
          Gastritis Etiology
          Ulcer Etiology
          Stomach Neoplasms Etiology
          Hydrocarbons, Chlorinated
          Methanol
          Bacterial Colonization Drug Effects
          Urease Drug Effects
          Flavonoids Pharmacodynamics
          Gastritis Prevention and Control
          Ulcer Prevention and Control
          Stomach Neoplasms Prevention and Control
          Human
      ab: "Quelites" are edible plants that are part of the traditional agro-ecosystems in Mexico. These plants, despite their already known nutritional properties, are now considered neglected and underutilized species. With the objective of promoting their reinsertion in the markets and mainly, in daily diets, efforts have been made to study them from multidisciplinary approaches to demonstrate their beneficial properties. To generate evidence of an added health-promoting value that would encourage quelites consumption, in the present work, the anti-Helicobacter pylori activity of three representative quelite species, Anoda cristata (Alache), Cnidoscolus aconitifolius (Chaya), and Crotalaria pumila (Chepil), was tested. H. pylori is considered the etiological agent of gastritis, ulcer, and gastric cancer, and represents a public health problem in Mexico and worldwide. Aqueous (AQ) and dichloromethane–methanol (DM) extracts were obtained from the three species of quelites to investigate their effect on H. pylori growth and on two of its colonization factors (adherence and urease activity). DM extracts from Chaya, Chepil, and Alache exert the best inhibitory effect on bacterial growth, with minimum inhibitory concentrations of 62.5, 125, and 250 μg/mL, respectively. AQ and DM extracts inhibit bacterial adhesion by 30% to 50%. None of them has an effect on urease activity. The two flavonoids present in A. cristata, acacetin and diosmetin, inhibit H. pylori growth by ∼90% with 3.9 μg/mL. These results provide new information about the anti-H. pylori potential of three edible quelites, and give an added value, since their routine consumption may impact on the prevention and/or control of H. pylori-associated diseases.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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