Does social cognition training augment response to computer-assisted cognitive remediation for schizophrenia?
Objectives: Cognitive remediation therapy (CRT) has shown significant improvement in cognition in schizophrenia. However, effect sizes of CRT have been reported to be modest raising the issue how to augment the effects of CRT on neurocognition and social cognition. Our aim was to examine whether the...
| Publicado en: | Schizophrenia Research Vol. 201; pp. 180 - 187 |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
Elsevier B.V.
Nov2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=133115522&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 133115522 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09209964 3PT jtl: Schizophrenia Research issn: 09209964 maglogo: N pubinfo: dt: Nov2018 vid: 201 pid: 1004 pub: Elsevier B.V. artinfo: ui: 133115522 133115522 NLM29910120 133115522 10.1016/j.schres.2018.06.012 NLM29910120 133115522 ppf: 180 ppct: 7 formats: tig: atl: Does social cognition training augment response to computer-assisted cognitive remediation for schizophrenia? aug: au: Lindenmayer, Jean-Pierre Khan, Anzalee McGurk, Susan R. Kulsa, Mila Kirstie C. Ljuri, Isidora Ozog, Veronica Fregenti, Samantha Capodilupo, Gianna Buccellato, Kiara Thanju, Amod Goldring, Abraham Parak, Mohan Parker, Benedicto affil: Manhattan Psychiatric Center, 600 East 125th Street Wards Island, New York, NY 10035, United States sug: subj: Cognition Psychotic Disorders Therapy Schizophrenia Rehabilitation Perception Therapy, Computer Assisted Psychotic Disorders Psychosocial Factors Male Treatment Outcomes Social Skills Young Adult Human Adult Psychology Middle Age Female Validation Studies Comparative Studies Evaluation Research Multicenter Studies Randomized Controlled Trials Random Assignment Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Objectives: Cognitive remediation therapy (CRT) has shown significant improvement in cognition in schizophrenia. However, effect sizes of CRT have been reported to be modest raising the issue how to augment the effects of CRT on neurocognition and social cognition. Our aim was to examine whether the addition of computerized social cognition training would enhance the effects on neurocognition and social cognition as compared to CRT alone.Methods: This is a 12-week, parallel group trial of 131 in- and out-patients with schizophrenia randomized to CRT (COGPACK or Brain Fitness) with computerized social cognition training (MRIGE), or CRT alone for 36 sessions. Participants were assessed at baseline and after 12 weeks of treatment. Assessments included neurocognition, social cognition, psychopathology, and functioning.Results: The combined intervention, CRT + MRIGE, showed greater improvements in the MCCB indices of Visual Learning, Working Memory, Reasoning and Problem-Solving, and the neurocognitive composite score compared to CRT alone (Bonferroni adjusted p = 0.004, p = 0.005, p = 0.01, respectively), as did social cognition measures (Bonferroni adjusted p = 0.006, p = 0.005, respectively).Conclusions: Supplementing CRT with computerized social cognition training produced greater benefits in neurocognition, including visual learning, memory, executive functions, and social cognition relative to cognitive training alone. These findings favoring the combined training may be contributed to both the greater overall amount of cognitive practice, as well as the specific cognitive functions engaged by the social cognition training. pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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