Noninvasive Ventilation as an Important Adjunct to an Exercise Training Program in Subjects With Moderate to Severe COPD.

BACKGROUND: The primary objective of this study was to investigate whether noninvasive ventilation (NIV) can positively affect exercise capacity, maximum oxygen uptake (...), and symptoms after a 6-week physical training program for subjects with moderate to very severe COPD. METHODS: 47 subjects wi...

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Publicado en:Respiratory Care Vol. 63; no. 11; pp. 1388 - 1399
Autores principales: Marrara, Kamilla Tays, Pires Di Lorenzo, Valéria Amorim, Jaenisch, Rodrigo B., Cabiddu, Ramona, de Oliveira Sato, Tatiana, Gonçalves Mendes, Renata, Oliveira, Claudio R., Costa, Dirceu, Borghi-Silva, Audrey
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Mary Ann Liebert, Inc. Nov2018
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Mary Ann Liebert, Inc.
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        atl: Noninvasive Ventilation as an Important Adjunct to an Exercise Training Program in Subjects With Moderate to Severe COPD.
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        au:
          Marrara, Kamilla Tays
          Pires Di Lorenzo, Valéria Amorim
          Jaenisch, Rodrigo B.
          Cabiddu, Ramona
          de Oliveira Sato, Tatiana
          Gonçalves Mendes, Renata
          Oliveira, Claudio R.
          Costa, Dirceu
          Borghi-Silva, Audrey
        affil: Cardiopulmonary Physiotherapy Laboratory, Federal University of São Carlos, São Carlos, São Paulo, Brazil
      sug:
        subj:
          Pulmonary Disease, Chronic Obstructive
          Noninvasive Procedures
          Respiration, Artificial
          Physical Education and Training
          Training Effect (Physiology)
          Human
          Prospective Studies
          Randomized Controlled Trials
          Random Assignment
          Treatment Outcomes
          Short Form-36 Health Survey (SF-36)
          Clinical Assessment Tools
          Brazil
          Exercise Test
          Respiratory Muscles
          Muscle Strength
          Chi Square Test
          Two-Way Analysis of Variance
          Data Analysis Software
          Male
          Female
          Middle Age
          Descriptive Statistics
          Aged
          Quality of Life
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: BACKGROUND: The primary objective of this study was to investigate whether noninvasive ventilation (NIV) can positively affect exercise capacity, maximum oxygen uptake (...), and symptoms after a 6-week physical training program for subjects with moderate to very severe COPD. METHODS: 47 subjects with COPD who were enrolled in a physical training program were randomized to either physical training alone or NIV + physical training (NIV-Physical training). Physical training consisted of dynamic aerobic exercises on a treadmill 3 times/week for 6 weeks, for a total of 18 sessions. NIV was titrated according to the subject's tolerance at rest and during exercise. Assessments included physiological responses and symptoms at the incremental cardiopulmonary exercise test peak and during submaximal exercise on a treadmill, 6-min walk distance, maximum inspiratory (PImax) and expiratory pressure (PEmax), BODE index, and health-related quality of life. RESULTS: 43 subjects completed the 6-week physical training program. Both groups improved 6-min walk distance, PImax, BODE index, and quality of life, and no differences were found between groups. However, significant improvements were observed for subjects in the NIV-Physical training group with regard to PEmax, maximum ..., maximum metabolic equivalents, circulatory power, and maximum ... CONCLUSIONS: A 6-week physical training program alone can improve tolerance for exercise and quality of life, in addition to reducing the risk of mortality. However, NIV associated with a physical training program was shown to have an additive beneficial effect on powerful prognostic markers (maximum ... and circulatory power) and to reduce symptoms and improve oxygen saturation in subjects with moderate to very severe COPD.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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