Extended two-stage adaptive designs with three target responses for phase II clinical trials.
We develop a nature-inspired stochastic population-based algorithm and call it discrete particle swarm optimization to find extended two-stage adaptive optimal designs that allow three target response rates for the drug in a phase II trial. Our proposed designs include the celebrated Simon's two-sta...
| Publicado en: | Statistical Methods in Medical Research Vol. 27; no. 12; pp. 3628 - 3643 |
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| Autores principales: | , |
| Formato: | algorithm equations & formulas research tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
Dec2018
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| Acceso en línea: | Ver este registro en EBSCOhost |