Risk assessment for preterm preeclampsia in first trimester: Comparison of three calculation algorithms.
Objective: To better adjust the risk for preeclampsia, multifactorial models in first trimester of pregnancy have found the way in clinical practice. This study compares the available test algorithms.Study Design: In a cross-sectional study between November 2013 and April 2016 we compared the tests...
| Published in: | European Journal of Obstetrics & Gynecology & Reproductive Biology Vol. 231; pp. 241 - 248 |
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| Main Authors: | , , , , , , , , , |
| Format: | research Journal Article |
| Published: |
Elsevier B.V.
Dec2018
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=133319433&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 133319433 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03012115 3KK jtl: European Journal of Obstetrics & Gynecology & Reproductive Biology issn: 03012115 maglogo: N pubinfo: dt: Dec2018 vid: 231 pid: 1004 pub: Elsevier B.V. artinfo: ui: 133319433 133319433 NLM30439653 133319433 10.1016/j.ejogrb.2018.11.006 NLM30439653 133319433 ppf: 241 ppct: 7 formats: tig: atl: Risk assessment for preterm preeclampsia in first trimester: Comparison of three calculation algorithms. aug: au: Lakovschek, Ioana C. Ulrich, Daniela Jauk, Stefanie Csapo, Bence Kolovetsiou-Kreiner, Vassiliki Mayer-Pickel, Karoline Stern, Christina Lang, Uwe Obermayer-Pietsch, Barbara Cervar-Zivkovic, Mila affil: Department of Obstetrics and Gynaecology, Division of Obstetrics, Medical University of Graz, Austria sug: subj: Pre-Eclampsia Etiology Pregnancy Trimester, First Prenatal Care Pregnancy Risk Factors Human Algorithms Female Risk Assessment Methods Pre-Eclampsia Diagnosis Adult Cross Sectional Studies Validation Studies Comparative Studies Evaluation Research Multicenter Studies Scales Adult: 19-44 years Female ab: Objective: To better adjust the risk for preeclampsia, multifactorial models in first trimester of pregnancy have found the way in clinical practice. This study compares the available test algorithms.Study Design: In a cross-sectional study between November 2013 and April 2016 we compared the tests results of three first trimester testing algorithms for preeclampsia in 413 women. Risk for preterm preeclampsia was calculated with three different algorithms: Preeclampsia Predictor™ Software by PerkinElmer (PERK), ViewPoint® Software by GE Healthcare (VP) and the online calculator of the Fetal Medicine Foundation (FMF).We analyzed the data descriptively and determined Cohen's Kappa to assess the agreement among the algorithms.Results: VP classified 89(21.5%) women, PERK 43(10.4%) women and FMF 90 (21.8%) women as having high risk for preterm preeclampsia (<34 weeks of gestation for VP and PERK and <37 weeks of gestation for FMF). Agreement between tests ranged from moderate to substantial (PERK/VP: κ = 0.56, PERK/ FMF: κ = 0.50, and VP/ FMF: κ = 0.72).Conclusion: The three algorithms are similar but not equal. This may depend on chosen cut off, but also on test properties. This study cannot decide which algorithm is the best, but differences in results and cut offs should be taken into account. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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