Dialysis is an independent risk factor for perioperative adverse events, readmission, reoperation, and mortality for patients undergoing elective spine surgery.
Background Context: The prevalence of dialysis-dependent patients in the United States is growing. Prior studies evaluating the risk of perioperative adverse events for dialysis-dependent patients are either institutional cohort studies limited by patient numbers or administrative database studies l...
| Published in: | Spine Journal Vol. 18; no. 11; pp. 2033 - 2043 |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Elsevier B.V.
Nov2018
|
| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=133478172&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 133478172 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15299430 KJX jtl: Spine Journal issn: 15299430 maglogo: N pubinfo: dt: Nov2018 vid: 18 iid: 11 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 133478172 133478172 NLM30077772 133478172 10.1016/j.spinee.2018.04.007 NLM30077772 133478172 ppf: 2033 ppct: 10 formats: tig: atl: Dialysis is an independent risk factor for perioperative adverse events, readmission, reoperation, and mortality for patients undergoing elective spine surgery. aug: au: Ottesen, Taylor D. McLynn, Ryan P. Zogg, Cheryl K. Shultz, Blake N. Ondeck, Nathaniel T. Bovonratwet, Patawut Bellamkonda, Kirthi S. Rubin, Lee E. Grauer, Jonathan N. affil: Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, 47 College St, New Haven, CT 06511, USA sug: subj: Hemodialysis Adverse Effects Surgery, Elective Adverse Effects Spine Surgery Postoperative Complications Epidemiology Aged Reoperation Statistics and Numerical Data Adult Patient Discharge Statistics and Numerical Data Female Male Postoperative Complications Mortality Readmission Statistics and Numerical Data Middle Age Funding Source Aged: 65+ years Adult: 19-44 years Middle Aged: 45-64 years Female Male ab: Background Context: The prevalence of dialysis-dependent patients in the United States is growing. Prior studies evaluating the risk of perioperative adverse events for dialysis-dependent patients are either institutional cohort studies limited by patient numbers or administrative database studies limited to inpatient data.Purpose: The present study uses a large, national sample with 30-day follow-up to investigate dialysis as risk factor for perioperative complications independent of patient demographics or comorbidities.Study Design/setting: This is a retrospective cohort study.Patient Sample: Patients undergoing elective spine surgery with or without dialysis from the 2005-2015 National Surgical Quality Improvement Program (NSQIP) database were included in the study.Outcome Measures: Postoperative complications within 30 days and binomial reoperation, readmission, and mortality within 30 days were determined.Methods: The 2005-2015 NSQIP databases were queried for adult dialysis-dependent and dialysis-independent patients undergoing elective spinal surgery. Differences in 30-day outcomes were compared using risk-adjusted multivariate regression and coarsened exact matching analysis for adverse events, unplanned readmission, reoperation, and mortality. The percentage of complications occurring before versus after hospital discharge was also assessed. The authors have no financial disclosures related to the present study.Results: A total of 467 dialysis and 173,311 non-dialysis patients met the inclusion criteria. Controlling for age, gender, body mass index, functional status, and American Society of Anesthesiologists (ASA) class, dialysis patients were found to be at significantly greater odds of any adverse event (odds ratio [OR]=2.52 before, 2.17 after matching, p=<.001), major adverse event (OR=2.90 before, 2.52 after matching, p=<.001), and minor adverse event (OR=1.50 before matching, p=<.025, but not significantly different after matching). Further, dialysis patients were significantly more likely to return to the operating room (OR=2.77 before, 2.50 after matching, p=<.001), have unplanned readmissions (OR=2.73 before, 2.37 after matching, p=<.001), and die within 30 days (OR=3.77 before, 2.71 after matching, p=<.001). Adverse events occurred after discharge for 51.78% of non-dialysis patients and for 43.80% of dialysis patients.Conclusions: Dialysis patients undergoing elective spine surgery are at significantly higher risk of aggregated adverse outcomes, return to the operating room, readmission, and death than non-dialysis patients, even after controlling for patient demographics and overall health (as indicated by ASA class). These differences need to be considered when determining treatment options. Additionally, with bundled payments expected in spine surgery, physicians and hospitals need to account for increased costs and liabilities when working with dialysis patients. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|