Multiobjective design optimization of stent geometry with wall deformation for triangular and rectangular struts.

The stent geometrical design (e.g., inter-strut gap, length, and strut cross-section) is responsible for stent-vessel contact problems and changes in the blood flow. These changes are crucial for causing some intravascular abnormalities such as vessel wall injury and restenosis. Therefore, structura...

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Publicado en:Medical & Biological Engineering & Computing Vol. 57; no. 1; pp. 15 - 27
Autores principales: Putra, Narendra Kurnia, Palar, Pramudita Satria, Anzai, Hitomi, Shimoyama, Koji, Ohta, Makoto
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Springer Nature Jan2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2019
      vid: 57
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      pub: Springer Nature
      place: New York, New York
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        atl: Multiobjective design optimization of stent geometry with wall deformation for triangular and rectangular struts.
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        au:
          Putra, Narendra Kurnia
          Palar, Pramudita Satria
          Anzai, Hitomi
          Shimoyama, Koji
          Ohta, Makoto
        affil: Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University, Aramaki-Aza Aoba 6-6-4, Aoba-ku, 980-8579, Sendai, Miyagi, Japan
      sug:
        subj:
          Stents
          Prosthesis Design
          Stress, Mechanical
          Hemodynamics
          Computer Simulation
          Models, Biological
          Scales
          Funding Source
      ab: The stent geometrical design (e.g., inter-strut gap, length, and strut cross-section) is responsible for stent-vessel contact problems and changes in the blood flow. These changes are crucial for causing some intravascular abnormalities such as vessel wall injury and restenosis. Therefore, structural optimization of stent design is necessary to find the optimal stent geometry design. In this study, we performed a multiobjective stent optimization for minimization of average stress and low wall shear stress ratio while considering the wall deformation in 3D flow simulations of triangular and rectangular struts. Surrogate-based optimization with Kriging method and expected hypervolume improvement (EHVI) are performed to construct the surrogate model map and find the best configuration of inter-strut gap (G) and side length (SL). In light of the results, G-SL configurations of 2.81-0.39 and 3.00-0.43 mm are suggested as the best configuration for rectangular and triangular struts, respectively. Moreover, considering the surrogate model and flow pattern conditions, we concluded that triangular struts work better to improve the intravascular hemodynamics. ᅟ Graphical abstract.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
        research
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        Journal Article
      ougenre: Article
    language: English
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