Fractal dimension based carotid plaque characterization from three-dimensional ultrasound images.
Irregularity of the plaque surface associated with previous plaque rupture plays an important role in the risk estimation of stroke caused by carotid atherosclerotic lesions. Thus, the aim of this study is to develop and validate novel vulnerability biomarkers from three-dimensional ultrasound (3DUS...
| Published in: | Medical & Biological Engineering & Computing Vol. 57; no. 1; pp. 135 - 147 |
|---|---|
| Main Authors: | , , , , |
| Format: | diagnostic images equations & formulas pictorial research Journal Article |
| Published: |
Springer Nature
Jan2019
|
| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=133800682&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 133800682 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: Jan2019 vid: 57 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 133800682 133800682 NLM30046955 133800682 10.1007/s11517-018-1865-5 NLM30046955 133800682 ppf: 135 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Fractal dimension based carotid plaque characterization from three-dimensional ultrasound images. aug: au: Zhou, Ran Luo, Yongkang Fenster, Aaron Spence, John David Ding, Mingyue affil: Medical Ultrasound Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, 430074, Wuhan, Hubei, China sug: subj: Imaging, Three-Dimensional Mathematics Atherosclerosis Carotid Arteries Ultrasonography Carotid Arteries Pathology Aged Pharmacokinetics ROC Curve Linear Regression Atherosclerosis Pathology Impact of Events Scale Funding Source Aged: 65+ years ab: Irregularity of the plaque surface associated with previous plaque rupture plays an important role in the risk estimation of stroke caused by carotid atherosclerotic lesions. Thus, the aim of this study is to develop and validate novel vulnerability biomarkers from three-dimensional ultrasound (3DUS) images by analyzing the surface morphological characteristics of carotid plaque using fractal geometry features. In the experiments, a total of 38 3DUS plaque images were obtained from two groups of patients treated with 80 mg of atorvastatin or placebo daily for 3 months respectively. Two types of 3D fractal dimensions (FDs) were used to describe the smoothness of plaque surface morphology and the roughness from intensity of 3DUS images. Student's t test showed that the two fractal features were effective for detecting the statin-related changes in carotid atherosclerosis with p < 0.00023 and p < 0.0113 respectively. It was concluded that the 3D FD measurements were effective for analyzing carotid plaque characteristics and especially effective for evaluating the impact of atorvastatin treatment. Graphical abstract ᅟ. pubtype: Academic Journal doctype: diagnostic images equations & formulas pictorial research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|