Validity of predictive equations for 24-h urinary potassium excretion based on timing of spot urine collection among adults: the MESA and CARDIA Urinary Sodium Study and NHANES Urinary Sodium Calibration Study.
Background: 24-h urine collections are the suggested method to measure daily urinary potassium excretion (uK) but are costly and burdensome to implement. Objective: This study tested howwell existing equations with the use of spot urine samples can estimate 24-h uK and if accuracy varies by timing o...
| Publicado en: | American Journal of Clinical Nutrition Vol. 108; no. 3; pp. 532 - 548 |
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| Autores principales: | , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Elsevier B.V.
Sep2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=133976997&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 133976997 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00029165 AJC jtl: American Journal of Clinical Nutrition issn: 00029165 maglogo: N pubinfo: dt: Sep2018 vid: 108 iid: 3 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 133976997 133976997 133976997 10.1093/ajcn/nqy138 133976997 ppf: 532 ppct: 16 formats: tig: atl: Validity of predictive equations for 24-h urinary potassium excretion based on timing of spot urine collection among adults: the MESA and CARDIA Urinary Sodium Study and NHANES Urinary Sodium Calibration Study. aug: au: Mercado, Carla I Cogswell, Mary E Loria, Catherine M Liu, Kiang Allen, Norrina Gillespie, Cathleen Wang, Chia-Yih Boer, Ian H de Wright, Jacqueline affil: Divisions of Diabetes Translation and National Center for Health Statistics, Centers for Disease Control and Prevention, Atlanta, GA sug: subj: Potassium Urine 24-hour Urine Collection Sodium Urine Potassium Metabolism Human Validity Predictive Value of Tests Calibration Age Factors Race Factors Sex Factors Cross Sectional Studies Adolescence Young Adult Adult District of Columbia Middle Age Aged Illinois Correlation Coefficient Adolescent: 13-18 years Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years ab: Background: 24-h urine collections are the suggested method to measure daily urinary potassium excretion (uK) but are costly and burdensome to implement. Objective: This study tested howwell existing equations with the use of spot urine samples can estimate 24-h uK and if accuracy varies by timing of spot urine collection, age, race, or sex. Design: This cross-sectional study used data from 407 participants aged 18–39 y from the Washington, DC area in 2011 and 554 participants aged 45–79 y from Chicago in 2013. Spot urine samples were collected in individual containers for 24 h, and 1 for each timed period (morning, afternoon, evening, and overnight) was selected. For each selected timed spot urine, 24-h uK was predicted through the use of published equations. Difference (bias) between predicted and measured 24-h uK was calculated for each timed period and within age, race, and sex subgroups. Individual-level differences were assessed through the use of Bland-Altman plots and correlation tests. Results: For all equations, regardless of the timing of spot urine, mean bias was usually significantly different than 0. No one prediction equation was unbiased across all sex, race, and age subgroups.With the use of the Kawasaki and Tanaka equations, 24-h uKwas overestimated at lowlevels and underestimated at high levels, whereas observed differential bias with the Mage equation was in the opposite direction. Depending on prediction equation and timing of urine sample, 61–75% of individual 24-h uKs were misclassified among 500-mg incremental categories from <1500 to ≥3000 mg. Correlations between predicted and measured 24-h uK were poor to moderate (0.19–0.71). Conclusion: Because predicted 24-h uK accuracy varies by timing of spot urine collection, published prediction equations, and within age-race-sex subgroups, study results making use of predicted 24- h uK in association with health outcomes should be interpreted with caution. It is possible that a more accurate prediction equation can be developed leading to different results. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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