Effect of Cilostazol on the Pharmacokinetics of Simvastatin in Healthy Subjects.

Purpose. We evaluated potential drug-drug interactions between cilostazol and simvastatin, both CYP3A substrates, in healthy subjects. Methods. An open-label, two-period, fixed-sequence clinical study was conducted. Seventeen subjects were given a single oral dose of simvastatin 40 mg on day 1 and m...

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Publicado en:BioMed Research International pp. 1 - 7
Autores principales: Kim, Jung-Ryul, Jung, Jin Ah, Kim, Seokuee, Huh, Wooseong, Ghim, Jong-Lyul, Shin, Jae-Gook, Ko, Jae-Wook
Formato: clinical trial research tables/charts Journal Article
Publicado: Wiley-Blackwell 1/9/2019
Acceso en línea:Ver este registro en EBSCOhost