Moving from the Trial to the Real World: Improving Medication Adherence Using Insights of Implementation Science.
Medication nonadherence is a serious public health concern. Although there are promising interventions that improve medication adherence, most interventions are developed and tested in tightly controlled research environments that are dissimilar from the real-world settings where the majority of pat...
| Publicado en: | Annual Review of Pharmacology & Toxicology Vol. 59; pp. 423 - 448 |
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| Autores principales: | , , , , |
| Formato: | review tables/charts Journal Article |
| Publicado: |
Annual Reviews Inc.
Jan2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=134051907&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 134051907 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03621642 26P jtl: Annual Review of Pharmacology & Toxicology issn: 03621642 maglogo: N pubinfo: dt: Jan2019 vid: 59 pid: 59 pub: Annual Reviews Inc. place: Palo Alto, California artinfo: ui: 134051907 134051907 134051907 10.1146/annurev-pharmtox-010818-021348 134051907 ppf: 423 ppct: 25 formats: tig: atl: Moving from the Trial to the Real World: Improving Medication Adherence Using Insights of Implementation Science. aug: au: Zullig, Leah L. Deschodt, Mieke Liska, Jan Bosworth, Hayden B. De Geest, Sabina affil: Center for Health Services Research in Primary Care, Durham Veterans Affairs Health Care System, Durham, North Carolina 27701, USA sug: subj: Medication Compliance Medical Practice Paradigms Research Personnel Physicians Policy Making Pharmaceutical Companies Health Care Delivery ab: Medication nonadherence is a serious public health concern. Although there are promising interventions that improve medication adherence, most interventions are developed and tested in tightly controlled research environments that are dissimilar from the real-world settings where the majority of patients receive health care. Implementation science methods have the potential to facilitate and accelerate the translation shift from the trial world to the real world. We demonstrate their potential by reviewing published, high-quality medication adherence studies that could potentially be translated into clinical practice yet lack essential implementation science building blocks. We further illustrate this point by describing an adherence study that demonstrates how implementation science creates a junction between research and real-world settings. This article is a call to action for researchers, clinicians, policy makers, pharmaceutical companies, and others involved in the delivery of care to adopt the implementation science paradigm in the scale-up of adherence (research) programs. pubtype: Academic Journal doctype: review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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