Development and prospective evaluation of CAPLET, a cancer ambulatory patient physical function longitudinal evaluation tool for routine clinical practice.
Purpose: A patient's physical function is a critical outcome variable for measuring and improving chronic care management. However, patient-reported outcome measures of physical function are not routinely assessed in cancer outpatients, in part due to limitations of tools available. This study prese...
| Publicado en: | Supportive Care in Cancer Vol. 27; no. 2; pp. 521 - 531 |
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| Autores principales: | , , , , , , , , , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Feb2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=134058494&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 134058494 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09414355 O1J jtl: Supportive Care in Cancer issn: 09414355 maglogo: N pubinfo: dt: Feb2019 vid: 27 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 134058494 134058494 NLM29982902 10.1007/s00520-018-4333-8 NLM29982902 134058494 ppf: 521 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Development and prospective evaluation of CAPLET, a cancer ambulatory patient physical function longitudinal evaluation tool for routine clinical practice. aug: au: Hall, Elizabeth Tam, Emily Liang, Mindy Zhang, Quihuang Liu, Lin Wong, Lauren Sarabia, Samantha Yeung, Sabrina Gill, Gursharan Eng, Lawson Perez-Cosio, Andrea Brown, M. Catherine Xu, Wei Li, Madeline Mittmann, Nicole Jones, Jennifer Howell, Doris Liu, Geoffrey affil: Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre and Departments of Medicine and Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada sug: subj: Disability Evaluation Neoplasms Diagnosis Quality of Life Psychosocial Factors Physical Examination Methods Adult Aged, 80 and Over Female Male Neoplasms Pathology Middle Age Young Adult Aged Cross Sectional Studies Prospective Studies Questionnaires Adult: 19-44 years Aged, 80 & over Middle Aged: 45-64 years Aged: 65+ years Female Male ab: Purpose: A patient's physical function is a critical outcome variable for measuring and improving chronic care management. However, patient-reported outcome measures of physical function are not routinely assessed in cancer outpatients, in part due to limitations of tools available. This study presents the development and evaluation of the Cancer Ambulatory Patient Physical Function Longitudinal Evaluation Tool (CAPLET) as an adaptive response tool for routinely screening for physical dysfunction in oncology clinical practice.Methods: In phase 1, 407 adult outpatients at Princess Margaret Cancer Centre completed the World Health Organization Disability Assessment Schedule (WHODAS) 2.0, Health Assessment Questionnaire Disability Index (HAQ-DI), EuroQuol-5D-3L ( EQ-5D-3L), and patient-reported outcome (PRO)-Eastern Cooperative Oncology Group (ECOG). CAPLET was developed based on a branching logic algorithm navigating patients to appropriate domains of HAQ-DI/WHOAS using their responses to the PRO-ECOG/EQ-5D-3L as screeners. Sensitivity/specificity of CAPLET screeners for HAQ-DI/WHODAS items were reported. In phase 2, CAPLET vs the WHODAS/HAQ-DI were alternatively administrated to 318 adult outpatients in a two-arm trial comparing time to completion and acceptability between the tools.Results: Using a patient's ECOG status and the sum of the mobility, self-care, and usual activity dimensions of the EQ-5D-3L to dichotomize patients as with or without difficulty, CAPLET achieved a sensitivity > 90% against recommended WHODAS and HAQ-DI cutoffs for significant dysfunction. Sensitivity of screeners for capturing dysfunction in individual WHODAS/HAQ-DI items ranged from 85 to 100%. Compared to the HAQ-DI/WHODAS, CAPLET was associated with a 50% reduction in administration times and improved patient acceptability, while reducing question burden by 84% for half the sample population.Conclusions: CAPLET improves the feasibility of capturing detailed assessments of patient-reported physical function in cancer outpatients. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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