Neural processing of food cues in pre‐pubertal children.

Summary: Background/Objectives: Neuroimaging investigations of brain pathways involved in reward and motivation have primarily focused on adults. This study sought to identify brain responses to visual food cues and explore its relationships with adiposity and sex in pre‐pubertal children. Methods:...

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Publicado en:Pediatric Obesity Vol. 14; no. 2
Autores principales: Luo, S., Alves, J., Hardy, K., Wang, X., Monterosso, J., Xiang, A. H., Page, K. A.
Formato: diagnostic images research tables/charts Journal Article
Publicado: Wiley-Blackwell Feb2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2019
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Neural processing of food cues in pre‐pubertal children.
      aug:
        au:
          Luo, S.
          Alves, J.
          Hardy, K.
          Wang, X.
          Monterosso, J.
          Xiang, A. H.
          Page, K. A.
        affil: Division of Endocrinology, Keck School of Medicine, University of Southern California, Los Angeles CA, USA
      sug:
        subj:
          Food Habits In Infancy and Childhood
          Brain Physiology
          Neural Pathways Physiology
          Cues
          Human
          Male
          Female
          Child
          Pediatric Obesity
          Sex Factors
          Brain Mapping
          Cerebral Cortex Physiology
          Reward
          Taste
          Appetite
          Emotions
          Memory
          Visual Perception
          Attention
          Adipose Tissue Distribution
          Hippocampus Physiology
          Frontal Lobe Physiology
          Child: 6-12 years
          Male
          Female
      ab: Summary: Background/Objectives: Neuroimaging investigations of brain pathways involved in reward and motivation have primarily focused on adults. This study sought to identify brain responses to visual food cues and explore its relationships with adiposity and sex in pre‐pubertal children. Methods: Brain responses to palatable food vs. non‐food cues were measured in 53 children (age: 8.18 ± .66 years; sex: 22 boys, 31 girls) after an overnight fast. Whole‐brain analysis (cluster‐correction Z > 2.3, P < .05) was performed to examine brain food cue reactivity and its relationships with adiposity and sex. Results: Greater brain activity in response to food vs. non‐food cues was observed in regions implicated in reward (orbital frontal cortex, striatum), taste (insula, postcentral gyrus), appetite (hypothalamus), emotion (amygdala), memory (hippocampus), visual processing (occipital cortex) and attention (parietal cortex). A negative association was found between percent body fat and food cue reactivity in the medial prefrontal cortex and lateral orbital frontal cortex adjusting for age and sex. Boys compared with girls had increased food cue reactivity in right hippocampus and visual cortex. Conclusions: These data suggest that body fat and sex are important moderators of brain food cue reactivity in children.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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