Analysis of the CDK4/6 Cell Cycle Pathway in Leiomyosarcomas as a Potential Target for Inhibition by Palbociclib.

Leiomyosarcoma (LMS) is characterized by high genomic complexity, and to date, no specific targeted therapy is available. In a genome-wide approach, we profiled genomic aberrations in a small cohort of eight primary tumours, two relapses, and eight metastases across nine different patients. We ident...

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Publicado en:	Sarcoma pp. 1 - 11
Autores principales:	Böhm, Michael J., Marienfeld, Ralf, Jäger, Daniela, Mellert, Kevin, von Witzleben, Adrian, Brüderlein, Silke, Wittau, Mathias, von Baer, Alexandra, Schultheiss, Markus, Mayer-Steinacker, Regine, Rücker, Frank G., Möller, Peter, Bullinger, Lars, Barth, Thomas F. E.
Formato:	pictorial research tables/charts Journal Article
Publicado:	Wiley-Blackwell 1/21/2019
Acceso en línea:	Ver este registro en EBSCOhost