Phosphocreatine Attenuates Isoproterenol-Induced Cardiac Fibrosis and Cardiomyocyte Apoptosis.

The present study was designed to further explore the role and the underlying molecular mechanism of phosphocreatine (PCr) for cardiac fibrosis in vivo. Isoproterenol (ISO) was used to induce cardiac fibrosis in rats. PCr administration ameliorated fibrosis by reducing collagen accumulation and fibr...

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Bibliographic Details
Published in:BioMed Research International pp. 1 - 8
Main Authors: Dai, Hui, Chen, Liang, Gao, Dongyue, Fei, Aihua
Format: pictorial research tables/charts Journal Article
Published: Wiley-Blackwell 1/8/2019
Online Access:View this record in EBSCOhost