Short-term QT interval variability in patients with coronary artery disease and congestive heart failure: a comparison with healthy control subjects.
This study aimed to test how different QT interval variability (QTV) indices change in patients with coronary artery disease (CAD) and congestive heart failure (CHF). Twenty-nine healthy volunteers, 29 age-matched CAD patients, and 20 age-matched CHF patients were studied. QT time series were derive...
| Published in: | Medical & Biological Engineering & Computing Vol. 57; no. 2; pp. 389 - 401 |
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| Main Authors: | , , , , , |
| Format: | equations & formulas research tables/charts Journal Article |
| Published: |
Springer Nature
Feb2019
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=134311231&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 134311231 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: Feb2019 vid: 57 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 134311231 134311231 NLM30143993 134311231 10.1007/s11517-018-1870-8 NLM30143993 134311231 ppf: 389 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Short-term QT interval variability in patients with coronary artery disease and congestive heart failure: a comparison with healthy control subjects. aug: au: Li, Yang Li, Peng Wang, Xinpei Karmakar, Chandan Liu, Changchun Liu, Chengyu affil: School of Control Science and Engineering, Shandong University, Jinan, People's Republic of China sug: subj: Heart Failure Physiopathology Long QT Syndrome Physiopathology Coronary Arteriosclerosis Physiopathology Heart Rate Physiology Aged Human Female Middle Age Male Electrocardiography Methods Adult Research Subjects Validation Studies Comparative Studies Evaluation Research Multicenter Studies Aged: 65+ years Middle Aged: 45-64 years Adult: 19-44 years Female Male ab: This study aimed to test how different QT interval variability (QTV) indices change in patients with coronary artery disease (CAD) and congestive heart failure (CHF). Twenty-nine healthy volunteers, 29 age-matched CAD patients, and 20 age-matched CHF patients were studied. QT time series were derived from 5-min resting lead-II electrocardiogram (ECG). Time domain indices [mean, SD, and QT variability index (QTVI)], frequency-domain indices (LF and HF), and nonlinear indices [sample entropy (SampEn), permutation entropy (PE), and dynamical patterns] were calculated. In order to account for possible influence of heart rate (HR) on QTV, all the calculations except QTVI were repeated on HR-corrected QT time series (QTc) using three correction methods (i.e., Bazett, Fridericia, and Framingham method). Results showed that CHF patients exhibited increased mean, increased SD, increased LF and HF, decreased T-wave amplitude, increased QTVI, and decreased PE, while showed no significant changes in SampEn. Interestingly, CHF patients also showed significantly changed distribution of the dynamical patterns with less monotonously changing patterns while more fluctuated patterns. In CAD group, only QTVI was found significantly increased as compared with healthy controls. Results after HR correction were in common with those before HR correction except for QTc based on Bazett correction. Graphical abstract Fig. The framework of this paper. The arrows show the sequential analysis of the data. pubtype: Academic Journal doctype: equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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