Noninvasively diagnosing for fetal trisomy 21 by examining heterozygous single nucleotide polymorphisms in the placental specific genes on chromosome 21.

Objective: Noninvasive prenatal diagnosing for fetal trisomy 21 could help to avoid unnecessary amniocentesis. It is feasible to target the cell-free placental-specific mRNA in maternal plasma, thus eliminating the interference from the maternal genetic background.Study Design: In this study, placen...

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Publicado en:European Journal of Obstetrics & Gynecology & Reproductive Biology Vol. 233; pp. 19 - 26
Autores principales: Zhou, Fan, Liu, Shanling, Wang, He
Formato: research tables/charts Journal Article
Publicado: Elsevier B.V. Feb2019
Acceso en línea:Ver este registro en EBSCOhost