Characterization of edema after cryo and radiofrequency ablations based on serial magnetic resonance imaging.
Introduction: Radiofrequency (RF) and cryoablation are routinely used to treat arrhythmias, but the extent and time course of edema associated with the two different modalities is unknown. Our goal was to follow the lesion maturation and edema formation after RF and cryoablation using serial magneti...
| Published in: | Journal of Cardiovascular Electrophysiology Vol. 30; no. 2; pp. 255 - 263 |
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| Main Authors: | , , , , , , , , |
| Format: | diagnostic images pictorial research tables/charts Journal Article |
| Published: |
Wiley-Blackwell
Feb2019
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=134535730&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 134535730 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10453873 GSB jtl: Journal of Cardiovascular Electrophysiology issn: 10453873 maglogo: Y pubinfo: dt: Feb2019 vid: 30 iid: 2 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 134535730 134535730 134535730 10.1111/jce.13785 134535730 ppf: 255 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Characterization of edema after cryo and radiofrequency ablations based on serial magnetic resonance imaging. aug: au: Yamashita, Kennosuke Kholmovski, Eugene Ghafoori, Elyar Kamali, Roya Kwan, Eugene Lichter, Justin MacLeod, Robert Dosdall, Derek J. Ranjan, Ravi affil: Department of Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City Utah sug: subj: Edema Diagnosis Edema Etiology Magnetic Resonance Imaging Methods Radiofrequency Ablation Adverse Effects Cryosurgery Adverse Effects Contrast Media Diagnostic Use Edema Pathology Human Edema Surgery ab: Introduction: Radiofrequency (RF) and cryoablation are routinely used to treat arrhythmias, but the extent and time course of edema associated with the two different modalities is unknown. Our goal was to follow the lesion maturation and edema formation after RF and cryoablation using serial magnetic resonance imaging (MRI). Methods and Results: Ventricular ablation was performed in a canine model (n = 11) using a cryo or an irrigated RF catheter. T2‐weighted (T2w) edema imaging and late gadolinium enhancement (LGE)‐MRI were done immediately (0 day: acute), 1 to 2 weeks (subacute), and 8 to 12 weeks (chronic) after ablation. After the final MRI, excised hearts underwent pathological evaluation. As a result, 45 ventricular lesions (cryo group: 20; RF group: 25) were evaluated. Acute LGE volume was not significantly different but acute edema volume in cryo group was significantly smaller (1225.0 ± 263.5 vs 1855.2 ± 520.5 mm3; P = 0.01). One week after ablation, edema still existed in both group but was similar in size. Two weeks after ablation there was no edema in either of the groups. In the chronic phase, the lesion volume for cryo and RF in LGE‐MRI (296.7 ± 156.4 vs 281.6 ± 140.8 mm3; P = 0.73); and pathology (243.3 ± 125.9 vs 214.5 ± 148.6 mm3; P = 0.49), as well as depth, was comparable. Conclusions: When comparing cryo and RF lesions of similar chronic size, acute edema is larger for RF lesions. Edema resolves in both cryo and RF lesions in 1 to 2 weeks. pubtype: Academic Journal doctype: diagnostic images pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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