Corneal oxidative damage in keratoconus cells due to decreased oxidant elimination from modified expression levels of SOD enzymes, PRDX6, SCARA3, CPSF3, and FOXM1.

Purpose: To compare the levels of gene expression for enzymes involved in production and elimination of reactive oxygen/nitrogen species (ROS/RNS) in normal human corneal cells (NL cells) with those in human corneal cells with keratoconus (KC cells) in vitro. Methods: Primary NL and KC stromal fibro...

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Bibliographic Details
Published in:Journal of Ophthalmic & Vision Research Vol. 14; no. 1; pp. 62 - 71
Main Authors: Atilano, Shari, Lee, Daniel, Fukuhara, Paula, Chwa, Marilyn, Nesburn, Anthony, Udar, Nitin, Kenney, Cristina
Format: pictorial research tables/charts Journal Article
Published: Knowledge E DMCC Jan-Mar2019
Online Access:View this record in EBSCOhost