A case of persistent fever, cutaneous manifestations and pulmonary and splenic nodules: clinical experience and a literature review.
Pyoderma gangrenosum (PG) is a rare and recurrent ulcerating, non‐infectious, inflammatory dermatosis, with occasional concomitant extracutaneous manifestations. The pathogenesis and aetiology of PG are unknown. Moreover, early diagnosis is challenging because there are several visceral manifestatio...
| Publicado en: | Internal Medicine Journal Vol. 49; no. 2; pp. 247 - 252 |
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| Autores principales: | , , , , |
| Formato: | case study diagnostic images pictorial Journal Article |
| Publicado: |
Wiley-Blackwell
Feb2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=134665751&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 134665751 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14440903 HYC jtl: Internal Medicine Journal issn: 14440903 maglogo: Y pubinfo: dt: Feb2019 vid: 49 iid: 2 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 134665751 134665751 134665751 10.1111/imj.14201 134665751 ppf: 247 ppct: 5 formats: tig: atl: A case of persistent fever, cutaneous manifestations and pulmonary and splenic nodules: clinical experience and a literature review. aug: au: Xu, Ping Cai, Yazhou Ying, Xiaona Shi, Shiqiao Song, Weidong affil: Department of Respiratory, Peking University Shenzhen Hospital, Shenzhen, Gangdong China sug: subj: Fever Splenic Diseases Lung Diseases Pyoderma Gangrenosum Symptoms Male Adult Chinese Persons Splenic Diseases Diagnosis Lung Diseases Diagnosis Radiography Methods Pyoderma Gangrenosum Diagnosis Adult: 19-44 years Male ab: Pyoderma gangrenosum (PG) is a rare and recurrent ulcerating, non‐infectious, inflammatory dermatosis, with occasional concomitant extracutaneous manifestations. The pathogenesis and aetiology of PG are unknown. Moreover, early diagnosis is challenging because there are several visceral manifestations that may occur prior to the skin findings, such that misdiagnosis of PG as an infection is common. Here, we present a case of PG in which pulmonary and spleen lesions preceded the cutaneous manifestations. The correct diagnosis was made 6 months after multiple nodules were detected in the lung and spleen, based on the development of skin wound ulcers. To the best of our knowledge, this is the first report of PG in which pulmonary and splenic involvement preceded the appearance of skin lesions, without systemic disease. The patient was followed up for 5 years, during which time complete clinical and radiographic resolution was confirmed. This case demonstrates the challenges in the diagnosis of PG and the importance of using multiple diagnostic methods to determine the cause of unexplained clinical manifestations. pubtype: Academic Journal doctype: case study diagnostic images pictorial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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