Efficiency of Sensorimotor Networks: Posture and Gait in Young and Older Adults.

Background/Study context: Posture and gait are complex sensorimotor functions affected by age. These difficulties are particularly apparent when performing cognitively demanding tasks. Characterizing the functional organization of brain networks involved in these associations remains a challenge bec...

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Publicado en:Experimental Aging Research Vol. 45; no. 1; pp. 41 - 57
Autores principales: Di Scala, G., Dupuy, M., Guillaud, E., Doat, E., Barse, E., Dillhareguy, B., Jean, F.A.M., Audiffren, M., Cazalets, J.R., Chanraud, S.
Formato: pictorial research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Jan/Feb2019
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Taylor & Francis Ltd
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        10.1080/0361073X.2018.1560108
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        atl: Efficiency of Sensorimotor Networks: Posture and Gait in Young and Older Adults.
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          Di Scala, G.
          Dupuy, M.
          Guillaud, E.
          Doat, E.
          Barse, E.
          Dillhareguy, B.
          Jean, F.A.M.
          Audiffren, M.
          Cazalets, J.R.
          Chanraud, S.
        affil: Institut de Neurosciences Cognitives et Intégratives d'Aquitaine (INCIA), Université de Bordeaux, CNRS-UMR 5287, Bordeaux, France
      sug:
        subj:
          Posture
          Gait Analysis In Adulthood
          Gait Analysis In Old Age
          Sensory Motor Integration
          Human
          Exploratory Research
          Adult
          Aged
          Diagnosis, Brain
          Magnetic Resonance Imaging Methods
          Motor Activity
          Adult: 19-44 years
          Aged: 65+ years
      ab: Background/Study context: Posture and gait are complex sensorimotor functions affected by age. These difficulties are particularly apparent when performing cognitively demanding tasks. Characterizing the functional organization of brain networks involved in these associations remains a challenge because of the incompatibility of brain imagery techniques with gross body movements. The present study aimed at testing whether resting-state functional connectivity of sensorimotor networks is associated with posture and gait performance recorded offline, in young and older adults. Methods: Young (n = 12, mean = 24.1 y/o) and older (n = 14, mean = 65.6 y/o) healthy adults were tested for stability of their posture and gait. Four hours later, anatomical and functional brain imaging data were collected with Magnetic Resonance Imaging (MRI). Bilateral precentral and postcentral gyri were used as seeds in a graph theory analysis focused on global and local efficiency. The possible association between these data and posture and gait performance was examined. Results: Both samples presented similar sensorimotor graphs, but with different global and local efficiencies (small world properties). The association between the networks' graph measures and posture and gait performance also differed across groups: local efficiency was correlated with gait stability in challenging conditions in older adults, but not in young adults. Conclusion: This exploratory study suggests that combining analyses of functional networks and offline body movement may provide important information about motor function. In older adults, the association between graph properties of the sensorimotor network and gait performance in challenging conditions may be indicative of compensatory processes. Prospective studies involving more subjects with a larger age range are warranted.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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