Fat trajectory after birth in very preterm infants mimics healthy term infants.

Summary: Background: Infants born very preterm experience poor postnatal growth relative to intrauterine growth, but at term equivalent age, they have increased percentage body fat compared with infants born at term. Objectives: The aim of this study was to assess body composition in very preterm in...

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Published in:Pediatric Obesity Vol. 14; no. 3
Main Authors: Al‐Theyab, N. A., Donovan, T. J., Eiby, Y. A., Colditz, P. B., Lingwood, B. E.
Format: research tables/charts Journal Article
Published: Wiley-Blackwell Mar2019
Online Access:View this record in EBSCOhost
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      dt: Mar2019
      vid: 14
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        134778876
        134778876
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        10.1111/ijpo.12472
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        atl: Fat trajectory after birth in very preterm infants mimics healthy term infants.
      aug:
        au:
          Al‐Theyab, N. A.
          Donovan, T. J.
          Eiby, Y. A.
          Colditz, P. B.
          Lingwood, B. E.
        affil: Centre for Clinical Research and Perinatal Research Centre, Faculty of Medicine, The University of Queensland, Brisbane Queensland, Australia
      sug:
        subj:
          Body Composition Evaluation
          Adipose Tissue Distribution In Infancy and Childhood
          Human
          Infant
          Infant, Premature
          Fat Free Mass
          Gestational Age
          Intensive Care Units, Neonatal
          Electrocardiography
          Infant: 1-23 months
      ab: Summary: Background: Infants born very preterm experience poor postnatal growth relative to intrauterine growth, but at term equivalent age, they have increased percentage body fat compared with infants born at term. Objectives: The aim of this study was to assess body composition in very preterm infants born before 32 weeks postmenstrual age and to compare this with infants born at 32–36 weeks of gestation. Methods: Percentage fat, fat mass and fat‐free mass were measured in 87 very preterm infants born <32 weeks of gestation and studied at 32–36 weeks and in 88 control infants born at 32–36 weeks of gestation and measured on days 2–5 postnatally. Results: At 32–36 weeks, very preterm infants were lighter and shorter, had significantly greater percentage fat and absolute fat mass and had a significantly lower absolute fat‐free mass than the control group. The trajectory in percentage fat over increasing postnatal age in very preterm infants was closely aligned to that in term infants. Conclusions: Infants born very preterm accumulate fat rapidly after birth and have a deficit in fat‐free mass. Fat accumulation may be triggered by birth or associated events. If this rapid fat accretion is not taken into account, assessment of growth based on weight alone will underestimate the deficit in fat‐free mass.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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