Preclinical Evaluation of a Novel TSPO PET Ligand 2-(7-Butyl-2-(4-(2-[18F]Fluoroethoxy)phenyl)-5-Methylpyrazolo[1,5-a]Pyrimidin-3-yl)-N,N-Diethylacetamide (18F-VUIIS1018A) to Image Glioma.

Purpose: There is an urgent need for the development of novel positron emission tomography (PET) tracers for glioma imaging. In this study, we developed a novel PET probe ([18F]VUIIS1018A) by targeting translocator protein (TSPO), an imaging biomarker for glioma. The purpose of this preclinical stud...

Descripción completa

Detalles Bibliográficos
Publicado en:Molecular Imaging & Biology Vol. 21; no. 1; pp. 113 - 122
Autores principales: Tang, Dewei, Li, Jun, Nickels, Michael L., Huang, Gang, Cohen, Allison S., Manning, H. Charles
Formato: research Journal Article
Publicado: Springer Nature Feb2019
Acceso en línea:Ver este registro en EBSCOhost